Swansea University - Institute of Life Science, The Francis Crick Institute, University of Bristol - Cellular and Molecular Medicine, University of Bristol - Cellular and Molecular Medicine, University of Bristol, Trinity College (Dublin) - Department of Molecular Rheumatology, Van Andel Institute - Department of Metabolism and Nutritional Programming, University of Birmingham - Institute of Immunology and Immunotherapy, University of Bristol - Cellular and Molecular Medicine, Swansea University - Institute of Life Science, Swansea University - Institute of Life Science, University College London - GOSH and Centre for Rheumatology Research, University of Birmingham - Institute of Immunology and Immunotherapy, University College Dublin (UCD), Swansea University - Institute of Life Science, The Francis Crick Institute, Trinity College (Dublin) - School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute - Department of Molecular Rheumatology, University of Dundee - Division of Cell Signaling and Immunology, University of Bristol - Cellular and Molecular Medicine, University of Bristol - Translational Health Sciences and Swansea University - Institute of Life Science