National Department of Health - Drug Resistant TB Directorate, McGill University - School of Population and Global Health, University of Cape Town (UCT) - Wellcome Centre for Infectious Disease Research in Africa, University of Cape Town (UCT) - Division of Clinical Pharmacology, Stellenbosch University, University of Cape Town (UCT), affiliation not provided to SSRN, Médecins Sans Frontières - Khayelitsha Project and Cape Town Mission, Northern Cape South Africa Centre for Tuberculosis, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, Amity Health Consortium, Klerksdorp-Tshepong Hospital Complex, University of the Witwatersrand - Reproductive Health and HIV Research Unit (RHRU), University of KwaZulu-Natal - Centre for the AIDS Programme of Research in South Africa (CAPRISA)University of the Witwatersrand - South African Medical Research Council and McGill University