Menno de Winther

University of Amsterdam - Amsterdam Cardiovascular Sciences

SCHOLARLY PAPERS

5

DOWNLOADS

166

TOTAL CITATIONS

1

Scholarly Papers (5)

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1.

The BNT162b2 mRNA SARS-CoV-2 Vaccine Induces Transient Afucosylated IgG1 in Naive But Not in Antigen-Experienced Vaccinees

Number of pages: 36 Posted: 08 Aug 2022
Julie Van Coillie, Tamas Pongracz, Johann Rahmöller, Hung-Jen Chen, Chiara E. Geyer, Lonneke A. van Vught, Jana S. Buhre, Tonći Šuštić, Thijs L. J. van Osch, Maurice Steenhuis, Willianne Hoepel, Wenjun Wang, Anne S. Lixenfeld, Jan Nouta, Sofie Keijzer, Federica Linty, Remco Visser, Mads D. Larsen, Emily L. Martin, Inga Künsting, Selina Lehrian, Vera von Kopylow, Carsten Kern, Hanna B. Lunding, Menno de Winther, Niels van Mourik, Theo Rispens, Tobias Graf, Marleen A. Slim, René P. Minnaar, Marije Bomers, Jonne J. Sikkens, Alexander P. J. Vlaar, C. Ellen van der Schoot, Jeroen den Dunnen, Manfred Wuhrer, Marc Ehlers, Gestur Vidarsson, Fatebenefratelli-Sacco Infectious Diseases Physicians Group and Amsterdam UMC COVID-19 S3/HCW Study Group
Sanquin Research - Department of Experimental Immunohematology, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Amsterdam - Center for Experimental and Molecular Medicine, University of Amsterdam - Center for Experimental and Molecular Medicine, University of Amsterdam - Center for Experimental and Molecular Medicine, affiliation not provided to SSRN, Sanquin Research, Sanquin Research, Sanquin Research - Department of Immunopathology, University of Amsterdam - Center for Experimental and Molecular Medicine, Leiden University, affiliation not provided to SSRN, affiliation not provided to SSRN, Sanquin Research - Department of Immunopathology, Sanquin Research, Sanquin Research, Sanquin Research, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Amsterdam - Amsterdam Cardiovascular Sciences, affiliation not provided to SSRN, Sanquin Research - Department of Immunopathology, affiliation not provided to SSRN, University of Amsterdam - Center for Experimental and Molecular Medicine, University of Amsterdam - University Medical Center, VU University Amsterdam - Department of Internal Medicine, VU University Amsterdam - Department of Internal Medicine, University of Amsterdam - Department of Intensive Care, Sanquin Research - Department of Experimental Immunohematology, University of Amsterdam - Center for Experimental and Molecular Medicine, Leiden University, University of Lübeck - Institute of Nutritional Medicine, Sanquin Research - Department of Immunopathology, Independent and Independent
Downloads 58 (795,004)
Citation 1

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mRNA vaccine, antibodies, glycosylation, fucosylation, COVID-19

2.

Integrated Metabolic-Transcriptomic Network Identifies Novel Immunometabolic Modulations in Human Macrophages

Number of pages: 28 Posted: 01 Dec 2023
Hung-Jen (Oliver) Chen, Johanna Vappiani, Guillermo R. Griffith, Lee M. Booty, Cindy P.A.A. van Roomen, Johan Kuiper, Jeroen den Dunnen, Wouter J. de Jonge, Rab K. Prinjha, Palwinder K. Mander, Daniel C. Sévin, Paola Grandi, Beata S. Wyspianska and Menno de Winther
University of Amsterdam - Amsterdam Cardiovascular Sciences, GlaxoSmithKline, University of Amsterdam - Amsterdam Cardiovascular Sciences, GlaxoSmithKline - GSK Stevenage, University of Amsterdam - Amsterdam Cardiovascular Sciences, Leiden University - Leiden Academic Centre for Drug Research, University of Amsterdam - Center for Experimental and Molecular Medicine, University of Amsterdam - Amsterdam University Medical Centers, GlaxoSmithKline - GSK Stevenage, GlaxoSmithKline - GSK Stevenage, GlaxoSmithKline, GlaxoSmithKline, GlaxoSmithKline - GSK Stevenage and University of Amsterdam - Amsterdam Cardiovascular Sciences
Downloads 37 (972,673)

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macrophage, metabolomics, multi-omics, immunometabolism, tryptophan metabolism, Fc receptor, cholesterol

3.

IL-10 Drives Glycolysis and Hinders Mitochondrial Pathways in Human Macrophages: Implications for Inflammatory Bowel Disease and Anti-TNF Treatment

Number of pages: 32 Posted: 13 Oct 2023
Hung-Jen (Oliver) Chen, Guillermo R. Griffith, Dyonne A.M. Lotgerink, Cindy P.A.A. van Roomen, Lee M. Booty, Michel van Weeghel, Daniel C. Sévin, H. Christian Eberl, Rab K. Prinjha, Wouter J. de Jonge, Gerald Drewes, Palwinder K. Mander, Paola Grandi, Beata S. Wyspianska and Menno de Winther
University of Amsterdam - Amsterdam Cardiovascular Sciences, University of Amsterdam - Amsterdam Cardiovascular Sciences, University of Amsterdam - Amsterdam Cardiovascular Sciences, University of Amsterdam - Amsterdam Cardiovascular Sciences, GlaxoSmithKline - GSK Stevenage, University of Amsterdam - University Medical Center, GlaxoSmithKline, GlaxoSmithKline, GlaxoSmithKline - GSK Stevenage, University of Amsterdam - Amsterdam University Medical Centers, GlaxoSmithKline, GlaxoSmithKline - GSK Stevenage, GlaxoSmithKline, GlaxoSmithKline - GSK Stevenage and University of Amsterdam - Amsterdam Cardiovascular Sciences
Downloads 32 (1,025,015)

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macrophages, interleukin-10, immunometabolism, inflammation, Innate immunity, OXPHOS

4.

Endothelial-to-Mesenchymal Transition Gene Signature Derived from Single-Cell Transcriptomics of Human Atherosclerotic Tissue Associates with Stable Plaque Histological Characteristics

Number of pages: 42 Posted: 31 Mar 2025
Gerard Pasterkamp, Lotte Slenders, Marian Wesseling, Siting Wei, Arjan Boltjes, Daniek M.C. Kapteijn, Petra van der Kraak, M Depuydt, Koen Prange, Noortje A.M. van den Dungen, Ernest Diez Benavente, Dominique de Kleijn, Gert Jan de Borst, Menno de Winther, Hester den Ruijter, Gary K. Owens and Michal Mokry
Utrecht University - University Medical Center (Utrecht), affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Princess Maxima Center for Pediatric Oncology, affiliation not provided to SSRN, Utrecht University - University Medical Center (Utrecht), affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Utrecht University - University Medical Center (Utrecht), Utrecht University - University Medical Center (Utrecht), Utrecht University - University Medical Center (Utrecht), University of Amsterdam - Amsterdam Cardiovascular Sciences, Utrecht University - University Medical Center (Utrecht), affiliation not provided to SSRN and Utrecht University - Department of Pediatric Gastroenterology
Downloads 22 (1,143,131)

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EndoMT, atherosclerosis, scRNA-seq, gene signature

5.

Identification of New Drugs to Counteract Anti-Spike IgG-Induced Hyperinflammation in Severe COVID-19

Number of pages: 30 Posted: 20 Jan 2023
Chiara E. Geyer, Hung-Jen Chen, Alexander P. Bye, Xue D. Manz, Denise Guerra, Tom G. Caniels, Tom PL Bijl, Guillermo R. Griffith, Willianne Hoepel, Steven W. de Taeye, Jennifer Veth, Alexander P. J. Vlaar, Amsterdam UMC COVID-19 Biobank, Gestur Vidarsson, Harm Jan Bogaard, Jurjan Aman, Jonathan M. Gibbins, Marit J. van Gils, Menno de Winther and Jeroen den Dunnen
University of Amsterdam - Center for Experimental and Molecular Medicine, University of Amsterdam - Center for Experimental and Molecular Medicine, University of Reading - School of Biological Sciences, University of Amsterdam - Department of Pulmonary Medicine, University of Amsterdam - Department of Medical Microbiology and Infection Prevention, University of Amsterdam - Department of Medical Microbiology and Infection Prevention, University of Amsterdam - Department of Medical Microbiology and Infection Prevention, University of Amsterdam - Amsterdam Cardiovascular Sciences, University of Amsterdam - Center for Experimental and Molecular Medicine, University of Amsterdam - Department of Medical Microbiology and Infection Prevention, University of Amsterdam - Center for Experimental and Molecular Medicine, University of Amsterdam - Department of Intensive Care, Independent, Sanquin Research - Department of Immunopathology, University of Amsterdam - Department of Pulmonary Medicine, University of Amsterdam - Department of Pulmonary Medicine, University of Reading - School of Biological Sciences, University of Amsterdam - Department of Medical Microbiology and Infection Prevention, University of Amsterdam - Amsterdam Cardiovascular Sciences and University of Amsterdam - Center for Experimental and Molecular Medicine
Downloads 17 (1,204,746)

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COVID-19 treatment, SYK, macrophage, FcR, entospletinib, Inflammation, IL-6, thrombosis, endothelial dysfunction, platelet