affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Arizona State University (ASU) - ASU-Banner Neurodegenerative Disease Research Center,, Banner Health - Civin Laboratory for Neuropathology, Banner Health - Civin Laboratory for Neuropathology, affiliation not provided to SSRN, The Translational Genomics Research Institute (TGen) - Division of Neurogenomics, Maastricht University - Department of Psychiatry and Psychology, School of Mental Health and Neuroscience, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Arizona State University (ASU), Arizona State University (ASU) - School of Molecular Sciences, University of Arizona and affiliation not provided to SSRN

Mayo Clinic - Department of Cancer Biology, Columbia University - Department of Pathology and Cell Biology, Columbia University - Irving Medical Center, Vanderbilt University - Department of Biochemistry, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Columbia University - Department of Pathology and Cell Biology, Columbia University - Department of Pathology and Cell Biology, University of Minnesota - Minneapolis - Department of Pharmaceutics, University of Minnesota - Minneapolis - Department of Pharmaceutics, University of Minnesota - Minneapolis - Department of Pharmaceutics, Mayo Clinic - Department of Cancer Biology, Mayo Clinic - Department of Neurosurgery, University of Minnesota - Minneapolis - Department of Pharmaceutics, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Vanderbilt University - Department of Biochemistry, Columbia University - Department of Systems Biology, Columbia University - Department of Pathology and Cell Biology and Mayo Clinic - Department of Cancer Biology

Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, University of California, San Francisco (UCSF), Massachusetts Institute of Technology (MIT), Massachusetts Institute of Technology (MIT), Pfizer Boulder Research & Development, Pfizer Boulder Research & Development, Massachusetts Institute of Technology (MIT), University of California, San Francisco (UCSF) and Massachusetts Institute of Technology (MIT) - Department of Biological Engineering