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Robertus Antonius Maria de Bruin

University College London - MRC LMCB - Laboratory for Molecular Cell Biology

Gower St

Kings Cross

London, WC1E 6BT

United Kingdom

  • University College London - MRC LMCB - Laboratory for Molecular Cell Biology

SCHOLARLY PAPERS

3

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Scholarly Papers (3)

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1.

Active Growth Signalling Promotes Senescence and Cancer Cell Sensitivity to CDK7 Inhibition

Number of pages: 39 Posted: 17 Oct 2022
Gemma Wilson, Georgina Sava, Karla Vuina, Caroline Huard, Leticia Meneguello, Jasmin Coulombe-Huntington, Thierry Bertomeu, Rory Maizels, Josh Lauring, Mike Tyers, Simak Ali, Cosetta Bertoli and Robertus Antonius Maria de Bruin
University College London - MRC LMCB - Laboratory for Molecular Cell Biology, Imperial College London - Division of Cancer, University College London - MRC LMCB - Laboratory for Molecular Cell Biology, University of Montreal - Department of Medicine, University College London - MRC LMCB - Laboratory for Molecular Cell Biology, University of Montreal - Department of Medicine, University of Montreal - Department of Medicine, University College London - MRC LMCB - Laboratory for Molecular Cell Biology, Johns Hopkins University - Sidney Kimmel Comprehensive Cancer Center, University of Montreal - Department of Medicine, Imperial College London - Division of Cancer, University College London - MRC LMCB - Laboratory for Molecular Cell Biology and University College London - MRC LMCB - Laboratory for Molecular Cell Biology
Downloads 45 (1,121,190)

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cell cycle, cell cycle arrest, cell cycle exit, Cyclin Dependent Kinase, CDK inhibition, CDK7 inhibitor, Senescence, cellular growth, proliferation, cancer biology, cancer treatment

2.

Oncogenic C-Myc Induces Replication Stress by Increasing Cohesins Chromatin Occupancy at Ctcf Sites

Number of pages: 39 Posted: 04 Feb 2022
Silvia Peripolli, Tanya Singh, Harshil Patel, Leticia Meneguello, Koshiro Kiso, Peter Thorpe, Cosetta Bertoli and Robertus Antonius Maria de Bruin
University College London, University College London, The Francis Crick Institute, University College London - MRC LMCB - Laboratory for Molecular Cell Biology, University College London, Queen Mary University of London, University College London - MRC LMCB - Laboratory for Molecular Cell Biology and University College London - MRC LMCB - Laboratory for Molecular Cell Biology
Downloads 32 (1,290,922)

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Oncogene-induced replication stress, c-Myc, cell cycle, cohesins, cancer, DNA damage, DNA replication

3.

c-Myc Regulates HSF1 to Coordinate Proteostasis and Genome Stability under Oncogenic Stress

Number of pages: 40 Posted: 02 Jul 2026
Joe Jones, Waratchaya Naksiang, Yahan Lei, Kiso Koshiro, John Labbadia, Cosetta Bertoli, Robertus Antonius Maria de Bruin and Sneak Peek Administrator
University College London, University College London, University College London, University College London, University College London, University College London, University College London - MRC LMCB - Laboratory for Molecular Cell Biology and Independent
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oncogene, c-Myc, HSF1, proteotoxic stress response, proteostasis, DNA damage response, genome instability