University College London - MRC LMCB - Laboratory for Molecular Cell Biology, Imperial College London - Division of Cancer, University College London - MRC LMCB - Laboratory for Molecular Cell Biology, University of Montreal - Department of Medicine, University College London - MRC LMCB - Laboratory for Molecular Cell Biology, University of Montreal - Department of Medicine, University of Montreal - Department of Medicine, University College London - MRC LMCB - Laboratory for Molecular Cell Biology, Johns Hopkins University - Sidney Kimmel Comprehensive Cancer Center, University of Montreal - Department of Medicine, Imperial College London - Division of Cancer, University College London - MRC LMCB - Laboratory for Molecular Cell Biology and University College London - MRC LMCB - Laboratory for Molecular Cell Biology