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Wei Zhang

Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute

20 Biopolis Way

138668

Singapore

  • Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute

SCHOLARLY PAPERS

2

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218

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0

Scholarly Papers (2)

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1.

Excellent Removal of Knob-into-Hole Bispecific Antibody Byproducts and Impurities in a Single Capture Chromatography

Number of pages: 20 Posted: 21 Mar 2022
Wei Zhang, Serene W. Chen, Kong Meng Hoi, Farouq Bin Mahfut and Yuansheng Yang
Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute and Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute
Downloads 112 (630,858)

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bispecific antibody, knob-into-hole, chromatography purification, low pH wash, hole-hole homodimer, aggregation propensity

2.

Mechanistic Insights: Harnessing Ceramic Hydroxyapatite as an Effective Polishing Strategy to Remove Product- and Process-Related Impurities in Bispecific Antibody Purification

Number of pages: 24 Posted: 29 Aug 2023
Nattha Ingavat, Xinhui Wang, Jia Min Liew, Farouq Bin Mahfut, Ka Pui But, Yee Jiun Kok, Xuezhi Bi, Yuansheng Yang, Kobayashi Shintaro, Maria Tsoumpra and Wei Zhang
Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute, affiliation not provided to SSRN, affiliation not provided to SSRN and Agency for Science, Technology and Research (A*STAR) - Bioprocessing Technology Institute
Downloads 106 (664,543)

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bispecific antibody, ceramic hydroxyapatite (CHT) chromatography, C-site cooperation, product- and process-related impurity removal, chromatography-induced aggregation