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Jun Li

Central South University

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Site-Specific N-Terminal Pegylation-Based Controlled Release of Biotherapeutics: An Application for Glp-1 Delivery to Improve Pharmacokinetics and Prolong Hypoglycemic Effects

Number of pages: 22 Posted: 28 Mar 2022
Qianmeng Lin, Xuan Xia, Jun Li, Zhan Zhou and Yongheng Chen
Central South University, Central South University, Central South University, Central South University - Research Center for Molecular Metabolomics and Central South University - NHC Key Laboratory of Cancer Proteomics & State Local Joint Engineering Laboratory for Anticancer Drugs
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Abstract:

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PEGylation, controlled release, site-specific modification, pharmacokinetics, GLP-1, hypoglycemic effect