Kansai Medical University - Department of Medical Chemistry, The University of Osaka - Institute for Protein Research, Kyushu University, The University of Osaka - Institute for Protein Research, Kyoto University - Graduate School of Medicine, The University of Osaka - Institute for Protein Research, Kansai Medical University - Department of Medical Chemistry, Kyoto University - Graduate School of Medicine, Kitami Institute of Technology - Graduated School of Biotechnology and Environmental Chemistry, University of Tsukuba - Life Science Center for Survival Dynamics, The University of Osaka - Institute for Protein Research, Kyoto University - Graduate School of Medicine and Kansai Medical University - Department of Medical Chemistry