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Likun Gong

Chinese Academy of Sciences (CAS) - Shanghai Institute of Materia Medica

SCHOLARLY PAPERS

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Scholarly Papers (3)

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1.

Ingenane Diterpenoids from Euphorbia Esula Play a Novel Role in Promoting Ldl Uptake Via Pcsk9-Ldlr Pathway

Number of pages: 28 Posted: 07 Aug 2024
Tong Chen, Yu Zhang, Pengju Guo, Aijun Hou, Yelin Duan, Yihan Chen, Jinting Liu, Jing Chen, Likun Gong and Lijiang Xuan
Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Nanjing University of Traditional Chinese Medicine, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Chinese Academy of Sciences (CAS) - Shanghai Institute of Materia Medica and Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research
Downloads 33 (1,304,549)

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Ingenane diterpenoids, LDL uptake, PCSK9, LDLR

2.

Next-Generation Anti-PD-L1/IL-15 Immunocytokine Elicits Superior Antitumor Immunity in Cold Tumors with Minimal Toxicity

Number of pages: 62 Posted: 13 Sep 2023
Wenqiang Shi, Nan Liu, Zexin Liu, Yuqi Yang, Qiongya Zeng, Yang Wang, Luyao Song, Junsheng Chen, Mingyuan Wu, Lin Zhou, Fengping Zhu, Likun Gong, Jianwei Zhu, Long Jiang and Huili Lu
Shanghai Jiao Tong University (SJTU) - Shanghai Frontiers Science Center for Drug Target Identification and Delivery, Chinese Academy of Sciences (CAS) - Shanghai Institute of Materia Medica, Shanghai Jiao Tong University (SJTU) - Shanghai Frontiers Science Center for Drug Target Identification and Delivery, Chinese Academy of Sciences (CAS) - Shanghai Institute of Materia Medica, Shanghai Jiao Tong University (SJTU) - Shanghai Frontiers Science Center for Drug Target Identification and Delivery, Shanghai Jiao Tong University (SJTU) - Shanghai Frontiers Science Center for Drug Target Identification and Delivery, Shanghai Jiao Tong University (SJTU) - Shanghai Frontiers Science Center for Drug Target Identification and Delivery, Shanghai Jiao Tong University (SJTU) - Engineering Research Center of Cell & Therapeutic Antibody, Shanghai Jiao Tong University (SJTU) - Engineering Research Center of Cell & Therapeutic Antibody, Shanghai Jiao Tong University (SJTU) - Department of Urology, National Center for Neurological Disorders, Chinese Academy of Sciences (CAS) - Shanghai Institute of Materia Medica, Shanghai Jiao Tong University (SJTU) - Engineering Research Center of Cell & Therapeutic Antibody, Shanghai Jiao Tong University (SJTU) - Shanghai Lung Cancer Center and Shanghai Jiao Tong University (SJTU) - Shanghai Frontiers Science Center for Drug Target Identification and Delivery
Downloads 27 (1,372,601)

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Immunotherapy, IL-15, immunocytokine, dose-limiting toxicities, prodrug, immune checkpoint inhibitors, resistance

3.

Screening of Stable Membranal CMTM6-PD-L1 Full-Length Complex to Evaluate the PD-1/PD-L1-CMTM6 Interaction and Develop Anti-Tumor Anti-CMTM6 Nanobody

Number of pages: 36 Posted: 08 Jun 2022
Xiaomin Jia, Yiru Long, Xiaolu Yu, Yongliang Tong, Runqiu Chen, Likun Gong and Yong Geng
Chinese Academy of Sciences (CAS) - CAS Key Laboratory of Receptor Research, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Chinese Academy of Sciences (CAS) - Shanghai Institute of Materia Medica and Chinese Academy of Sciences (CAS) - CAS Key Laboratory of Receptor Research
Downloads 27 (1,385,945)

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CMTM6, PD-L1, CMTM6-PD-L1 complex, membrane mimetic, nanobody