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Nan Liu

Chinese Academy of Sciences (CAS) - Shanghai Institute of Materia Medica

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Next-Generation Anti-PD-L1/IL-15 Immunocytokine Elicits Superior Antitumor Immunity in Cold Tumors with Minimal Toxicity

Number of pages: 62 Posted: 13 Sep 2023
Wenqiang Shi, Nan Liu, Zexin Liu, Yuqi Yang, Qiongya Zeng, Yang Wang, Luyao Song, Junsheng Chen, Mingyuan Wu, Lin Zhou, Fengping Zhu, Likun Gong, Jianwei Zhu, Long Jiang and Huili Lu
Shanghai Jiao Tong University (SJTU) - Shanghai Frontiers Science Center for Drug Target Identification and Delivery, Chinese Academy of Sciences (CAS) - Shanghai Institute of Materia Medica, Shanghai Jiao Tong University (SJTU) - Shanghai Frontiers Science Center for Drug Target Identification and Delivery, Chinese Academy of Sciences (CAS) - Shanghai Institute of Materia Medica, Shanghai Jiao Tong University (SJTU) - Shanghai Frontiers Science Center for Drug Target Identification and Delivery, Shanghai Jiao Tong University (SJTU) - Shanghai Frontiers Science Center for Drug Target Identification and Delivery, Shanghai Jiao Tong University (SJTU) - Shanghai Frontiers Science Center for Drug Target Identification and Delivery, Shanghai Jiao Tong University (SJTU) - Engineering Research Center of Cell & Therapeutic Antibody, Shanghai Jiao Tong University (SJTU) - Engineering Research Center of Cell & Therapeutic Antibody, Shanghai Jiao Tong University (SJTU) - Department of Urology, National Center for Neurological Disorders, Chinese Academy of Sciences (CAS) - Shanghai Institute of Materia Medica, Shanghai Jiao Tong University (SJTU) - Engineering Research Center of Cell & Therapeutic Antibody, Shanghai Jiao Tong University (SJTU) - Shanghai Lung Cancer Center and Shanghai Jiao Tong University (SJTU) - Shanghai Frontiers Science Center for Drug Target Identification and Delivery
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Abstract:

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Immunotherapy, IL-15, immunocytokine, dose-limiting toxicities, prodrug, immune checkpoint inhibitors, resistance