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Francesca De Franco

TES Pharma Srl

SCHOLARLY PAPERS

3

DOWNLOADS

246

TOTAL CITATIONS

1

Scholarly Papers (3)

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1.

Targeting Rad51-Brca2 Interaction to Induce Synthetic Lethality with Olaparib in Pancreatic Cancer: Development of a Novel Series of Phenyl Furan-Quinoline-Carboxylic Acids

Number of pages: 46 Posted: 05 Dec 2024
Giovanni Ferrandi, Greta Bagnolini, Laura Poppi, Mirco Masi, Viola Previtali, Angela Andonaia, Giulia Varignani, Francesca De Franco, Federico Falchi, Giuseppina Di Stefano, Stefania Girotto, Marinella Roberti and Andrea Cavalli
University of Bologna, University of Bologna, University of Bologna, Istituto Italiano di Tecnologia, Istituto Italiano di Tecnologia, affiliation not provided to SSRN, University of Bologna, TES Pharma Srl, University of Bologna, University of Bologna, Istituto Italiano di Tecnologia, University of Bologna and affiliation not provided to SSRN
Downloads 118 (617,542)

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Synthetic lethality, RAD51-BRCA2, protein-protein interaction inhibitors, small molecules, pancreatic cancer

2.

An 19f Nmr Fragment-Based Approach for the Discovery and Development of Brca2-Rad51 Inhibitors to Pursuit Synthetic Lethality in Combination with Parp Inhibition in Pancreatic Cancer

Number of pages: 45 Posted: 09 Nov 2023
Samuel Myers, Laura Poppi, Francesco Rinaldi, Marina Veronesi, Andrea Ciamarone, Viola Previtali, Greta Bagnolini, Fabrizio Schipani, Jose Antonio Ortega Martínez, Stefania Girotto, Giuseppina Di Stefano, Fulvia Farabegoli, Naomi Walsh, Francesca De Franco, Marinella Roberti and Andrea Cavalli
Istituto Italiano di Tecnologia, University of Bologna, Istituto Italiano di Tecnologia, Istituto Italiano di Tecnologia, Istituto Italiano di Tecnologia, Istituto Italiano di Tecnologia, University of Bologna, Istituto Italiano di Tecnologia, Istituto Italiano di Tecnologia, Istituto Italiano di Tecnologia, University of Bologna, University of Bologna, Dublin City University, TES Pharma Srl, University of Bologna and affiliation not provided to SSRN
Downloads 69 (899,324)
Citation 1

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Synthetic lethality, BRCA2-RAD51, PARP inhibition, NMR fragment-based screening, pancreatic cancer

3.

Development of 3α,7α-Dihydroxy-6α-ethyl-24-nor-5b-Cholan-23-Sulfate Sodium Salt (INT-767): Process Optimization, Synthesis and Characterization of Metabolites

Number of pages: 52 Posted: 21 Jun 2022
Bruno Cerra, Francesco Venturoni, Maria Souma, Giada Ceccarelli, Anna Maria Lozza, Daniela Passeri, Francesca De Franco, Ian R. Baxendale, Roberto Pellicciari, Antonio Macchiarulo and Antimo Gioiello
University of Perugia - Laboratory of Medicinal and Advanced Synthetic Chemistry, University of Perugia - Laboratory of Medicinal and Advanced Synthetic Chemistry, University of Perugia - Laboratory of Medicinal and Advanced Synthetic Chemistry, University of Perugia - Laboratory of Medicinal and Advanced Synthetic Chemistry, University of Perugia - Laboratory of Medicinal and Advanced Synthetic Chemistry, TES Pharma Srl, TES Pharma Srl, Durham University - Department of Chemistry, TES Pharma Srl, University of Perugia - Department of Pharmaceutical Sciences and University of Perugia - Laboratory of Medicinal and Advanced Synthetic Chemistry
Downloads 59 (980,173)

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Bile acid, flow chemistry, FXR, metabolites, ozonolysis, process chemistry, scale-up, sulfates