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Giuseppina Di Stefano

University of Bologna

SCHOLARLY PAPERS

2

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184

TOTAL CITATIONS

1

Scholarly Papers (2)

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1.

Targeting Rad51-Brca2 Interaction to Induce Synthetic Lethality with Olaparib in Pancreatic Cancer: Development of a Novel Series of Phenyl Furan-Quinoline-Carboxylic Acids

Number of pages: 46 Posted: 05 Dec 2024
Giovanni Ferrandi, Greta Bagnolini, Laura Poppi, Mirco Masi, Viola Previtali, Angela Andonaia, Giulia Varignani, Francesca De Franco, Federico Falchi, Giuseppina Di Stefano, Stefania Girotto, Marinella Roberti and Andrea Cavalli
University of Bologna, University of Bologna, University of Bologna, Istituto Italiano di Tecnologia, Istituto Italiano di Tecnologia, affiliation not provided to SSRN, University of Bologna, TES Pharma Srl, University of Bologna, University of Bologna, Istituto Italiano di Tecnologia, University of Bologna and affiliation not provided to SSRN
Downloads 116 (617,542)

Abstract:

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Synthetic lethality, RAD51-BRCA2, protein-protein interaction inhibitors, small molecules, pancreatic cancer

2.

An 19f Nmr Fragment-Based Approach for the Discovery and Development of Brca2-Rad51 Inhibitors to Pursuit Synthetic Lethality in Combination with Parp Inhibition in Pancreatic Cancer

Number of pages: 45 Posted: 09 Nov 2023
Samuel Myers, Laura Poppi, Francesco Rinaldi, Marina Veronesi, Andrea Ciamarone, Viola Previtali, Greta Bagnolini, Fabrizio Schipani, Jose Antonio Ortega Martínez, Stefania Girotto, Giuseppina Di Stefano, Fulvia Farabegoli, Naomi Walsh, Francesca De Franco, Marinella Roberti and Andrea Cavalli
Istituto Italiano di Tecnologia, University of Bologna, Istituto Italiano di Tecnologia, Istituto Italiano di Tecnologia, Istituto Italiano di Tecnologia, Istituto Italiano di Tecnologia, University of Bologna, Istituto Italiano di Tecnologia, Istituto Italiano di Tecnologia, Istituto Italiano di Tecnologia, University of Bologna, University of Bologna, Dublin City University, TES Pharma Srl, University of Bologna and affiliation not provided to SSRN
Downloads 68 (899,324)
Citation 1

Abstract:

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Synthetic lethality, BRCA2-RAD51, PARP inhibition, NMR fragment-based screening, pancreatic cancer