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Guoning Zhang

Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology

SCHOLARLY PAPERS

3

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121

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Scholarly Papers (3)

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1.

Rational Design, Synthesis, and Evaluating Primary Biological Activities of Novel Hiv-1 Protease Inhibitors Containing Heteraryl Acetamides as the P2 Ligands

Number of pages: 33 Posted: 05 Jun 2025
Yucheng Wang, Sihan Meng, Yu Gao, Qingqing Yang, Ling Ma, Biao Dong, Juxian Wang, Guoning Zhang, Minghua Wang, Shan Cen, Mei Zhu and Qi Shan
Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - CAMS Key Laboratory of Antiviral Drug Research, affiliation not provided to SSRN, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN and Tianjin Institute of Pharmaceutical Research
Downloads 49 (1,074,648)

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HIV-1 protease inhibitors, phenylacetamide derivatives, enzymatic inhibitory activity, antiviral activity, darunavir-resistant HIV-1 variant

2.

Discovery and Rational Optimization of 2, 2'-((1h-Indole-2,3-Diyl) Bis (Thio))Diacetamide as Novel Sars-Cov-2 Rdrp Inhibitors

Number of pages: 26 Posted: 09 Jan 2025
Yu-cheng Wang, Yu Shi, Jianyuan Zhao, Min Li, Liya Wei, Qi Shan, Minghua Wang, Mei Zhu, Shan Cen, Guoning Zhang and Juxian Wang
Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology, affiliation not provided to SSRN, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology, affiliation not provided to SSRN, affiliation not provided to SSRN, Tianjin Institute of Pharmaceutical Research, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology and affiliation not provided to SSRN
Downloads 40 (1,183,237)

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COVID-19, RdRp inhibitor, Non-nucleoside inhibitor, 2, 2'-((1H-indole-2, 3-diyl) bis (thio)) diacetamide derivatives

3.

Synthesis and Biological Evaluation of Novel N, N′-Diarylurea Derivatives as Potent Antibacterial Agents Against MRSA

Number of pages: 12 Posted: 27 Jun 2022
Xiaonan Du, Minghua Wang, Xinxin Hu, Tongying Nie, Mei Zhu, Guoning Zhang, Xuefu You, Yucheng Wang and Yu-cheng Wang
Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology and Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Biotechnology
Downloads 32 (1,290,922)

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N, N'-diarylurea, Antibacterial, Structure-activity relationship, MRSA