Kyushu University - Department of Cardiovascular Medicine, Kyushu University - Department of Cardiovascular Medicine, Kyushu University - Center for Clinical and Translational Research, International University of Health and Welfare Hospital (IUHW) - Pulmonary Hypertension Center, Kyushu University - Center for Clinical and Translational Research, Kyushu University - Center for Clinical and Translational Research, Kobe University - Division of Cardiovascular Medicine, Kyorin University - Department of Cardiovascular Medicine, Nagoya University - Department of Cardiology, Hokkaido University - Division of Respiratory and Cardiovascular Innovative Research, Tokyo Medical University - Department of Cardiology, National Cerebral and Cardiovascular Centre - Division of Pulmonary Circulation, Toho University - Ohashi Medical Center, Toho University - Division of Cardiovascular Medicine, National Hospital Organization, Osaka National Hospital, Department of Cardiology, Keio University - Department of Cardiology, National Cerebral and Cardiovascular Centre - Division of Pulmonary Circulation, Tokyo Medical University - Department of Cardiovascular Surgery, Kurume University - Division of Cardiovascular Medicine, Chibaken Saiseikai Narashino Hospital - Pulmonary Hypertension Center, National Hospital Organization Okayama Medical Centre - Department of Cardiology, Keio University - Department of Cardiology, Chiba University - Department of Respirology and Kyushu University - Department of Cardiovascular Medicine

Kurume University - Division of Cardiovascular Medicine, Fujita Health University, Kurume University - Division of Cardiovascular Medicine, Kurume University - Division of Cardiovascular Medicine, University of Tokyo, University of Tokyo, University of Tokyo - Department of Biostatistics, Kurume University - Division of Cardiovascular Medicine, Fujita Health University, International University of Health and Welfare, Tokyo, Juntendo University - Graduate School of Medicine, Caress Sapporo Hokko Memorial Clinic, Shiga University of Medical Science, Yokohama City University - Division of Cardiology, Nihon University, School of Medicine, Department of Internal Medicine, Division of Cardiology, Kumamoto University, Juntendo University - Department of Cardiovascular Biology and Medicine, Juntendo University - Department of Cardiovascular Biology and Medicine, Tohoku University Graduate School of Medicine - Department of Cardiovascular Medicine, Chiba University, Kyoto University - Graduate School of Medicine, St. Hill Hospital and Jichi Medical University

affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Tsuchiura Kyodo Hospital - Cardiovascular Medicine, affiliation not provided to SSRN, Wakayama Medical University - Department of Cardiovascular Medicine, Wakayama Medical University - Department of Cardiovascular Medicine, affiliation not provided to SSRN, affiliation not provided to SSRN, Kurume University - Division of Cardiovascular Medicine, Kurume University - Division of Cardiovascular Medicine, Teikyo University, affiliation not provided to SSRN and affiliation not provided to SSRN