University of Cape Town (UCT) - Department of Statistical Sciences, Imperial College London - National Heart and Lung Institute, University of Cape Town (UCT) - Department of Statistical Sciences, The University of Western Australia - Division of Infection and Immunity, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Bristol - MRC Integrative Epidemiology Unit, University of Cape Town (UCT) - Neuroscience Institute, Imperial College London - National Heart and Lung Institute and University of Cape Town (UCT) - Department of Pediatrics and Child Health