Malaria Consortium, UK Health Security Agency, PATH, Government of the United Kingdom - NHS Greater Glasgow and Clyde, London School of Hygiene & Tropical Medicine - Medical Research Council Unit The Gambia, London School of Hygiene & Tropical Medicine, affiliation not provided to SSRN, University of Cape Town, Division of Clinical Pharmacology, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Melbourne, University of Melbourne, University of Copenhagen, University of Copenhagen, Institute for Immunology and Microbiology, Centre for Medical Parasitology, London School of Hygiene & Tropical Medicine, London School of Hygiene & Tropical Medicine, University of Copenhagen, Institute for Immunology and Microbiology, Centre for Medical Parasitology, London School of Hygiene & Tropical Medicine, Faculty of Infectious & Tropical Diseases, Department of Disesae Control, London School of Hygiene & Tropical Medicine, Malaria Consortium and Malaria Consortium

University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Cape Town (UCT) - Department of Statistical Sciences, University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, Semmelweis University, Curtin University, University of Queensland - Child Health Research Centre, The University of Western Australia - Division of Infection and Immunity, University of Cape Town (UCT) - Neuroscience Institute, Imperial College London, Imperial College London - National Heart and Lung Institute and University of Cape Town (UCT) - Department of Statistical Sciences

University of Cape Town (UCT) - Division of Medical Microbiology, The University of Hong Kong, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT), Stellenbosch University, University of Cape Town (UCT), J. Craig Venter Institute, Maryland, J. Craig Venter Institute, Maryland, University of Cape Town (UCT) - Division of Medical Microbiology, University of Cape Town (UCT) - Division of Medical Microbiology, University of Cape Town (UCT) - Department of Molecular and Cell Biology, University of Cape Town (UCT) - Division of Medical Microbiology, University of Cape Town (UCT) - Division of Medical Microbiology, University of Cape Town (UCT) - Department of Pediatrics and Child Health and The University of Western Australia - Division of Infection and Immunity

University of Cape Town (UCT) - Department of Pediatrics and Child Health, Perth Children’s Hospital - Telethon Kids Institute, University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, Semmelweis University, University of Cape Town (UCT) - Department of Pediatrics and Child Health and University of Cape Town (UCT) - Department of Pediatrics and Child Health

University of Cape Town (UCT) - Department of Statistical Sciences, Imperial College London - National Heart and Lung Institute, University of Cape Town (UCT) - Department of Statistical Sciences, The University of Western Australia - Division of Infection and Immunity, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Bristol - MRC Integrative Epidemiology Unit, University of Cape Town (UCT) - Neuroscience Institute, Imperial College London - National Heart and Lung Institute and University of Cape Town (UCT) - Department of Pediatrics and Child Health

University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University College London - Great Ormond Street Institute of Child Health Biomedical Research Centre, University College London - Great Ormond Street Institute of Child Health Biomedical Research Centre, University of Cape Town (UCT) - Department of Pediatrics and Child Health, The University of Western Australia - Division of Infection and Immunity, London School of Hygiene & Tropical Medicine, London School of Hygiene & Tropical Medicine and University College London - Great Ormond Street Institute of Child Health Biomedical Research Centre

University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - Department of Pediatrics and Child Health, Cytel Inc., University of Cape Town (UCT) - Division of Epidemiology & Biostatistics, Cytel Inc. and The University of Western Australia - Division of Infection and Immunity

University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Red Cross War Memorial Children’s Hospital, University of Cape Town (UCT) - Groote Schuur Hospital, University of Cape Town (UCT) - Groote Schuur Hospital, University of Cape Town (UCT) - Groote Schuur Hospital, University of Cape Town (UCT) - Groote Schuur Hospital, University of Cape Town (UCT) - Red Cross War Memorial Children’s Hospital, University of Cape Town (UCT) - Red Cross War Memorial Children’s Hospital, University of Cape Town (UCT) - Department of Paediatric Rheumatology, University of Cape Town (UCT) - Red Cross War Memorial Children’s Hospital, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, University of the Witwatersrand, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University College London - Great Ormond Street Institute of Child Health Biomedical Research Centre, University College London - Great Ormond Street Institute of Child Health Biomedical Research Centre, University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Cape Town (UCT) - Department of Medicine, South African Medical Research Council, University of Cape Town (UCT) - Department of Paediatric Rheumatology, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine and Independent