University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University College London - Great Ormond Street Institute of Child Health Biomedical Research Centre, University College London - Great Ormond Street Institute of Child Health Biomedical Research Centre, University of Cape Town (UCT) - Department of Pediatrics and Child Health, The University of Western Australia - Division of Infection and Immunity, London School of Hygiene & Tropical Medicine, London School of Hygiene & Tropical Medicine and University College London - Great Ormond Street Institute of Child Health Biomedical Research Centre

University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - Department of Pediatrics and Child Health, Cytel Inc., University of Cape Town (UCT) - Division of Epidemiology & Biostatistics, Cytel Inc. and The University of Western Australia - Division of Infection and Immunity

University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Red Cross War Memorial Children’s Hospital, University of Cape Town (UCT) - Groote Schuur Hospital, University of Cape Town (UCT) - Groote Schuur Hospital, University of Cape Town (UCT) - Groote Schuur Hospital, University of Cape Town (UCT) - Groote Schuur Hospital, University of Cape Town (UCT) - Red Cross War Memorial Children’s Hospital, University of Cape Town (UCT) - Red Cross War Memorial Children’s Hospital, University of Cape Town (UCT) - Department of Paediatric Rheumatology, University of Cape Town (UCT) - Red Cross War Memorial Children’s Hospital, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, University of the Witwatersrand, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University of Cape Town (UCT) - SA-MRC Unit on Child & Adolescent Health, University College London - Great Ormond Street Institute of Child Health Biomedical Research Centre, University College London - Great Ormond Street Institute of Child Health Biomedical Research Centre, University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Cape Town (UCT) - Department of Medicine, South African Medical Research Council, University of Cape Town (UCT) - Department of Paediatric Rheumatology, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine and Independent