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Roisin McManus

German Center for Neurodegenerative Diseases (DZNE)

SCHOLARLY PAPERS

2

DOWNLOADS

195

TOTAL CITATIONS

6

Scholarly Papers (2)

1.

NLRP3-Mediated Glutaminolysis Regulates Microglia in Alzheimer's Disease

Number of pages: 60 Posted: 03 Aug 2022
German Center for Neurodegenerative Diseases (DZNE), German Center for Neurodegenerative Diseases (DZNE), German Center for Neurodegenerative Diseases (DZNE), German Center for Neurodegenerative Diseases (DZNE), University of Bonn - Institute of Innate Immunity, German Center for Neurodegenerative Diseases (DZNE), Technology University of Braunschweig - Department of Bioinformatics and Biochemistry, German Center for Neurodegenerative Diseases (DZNE), German Center for Neurodegenerative Diseases (DZNE), German Center for Neurodegenerative Diseases (DZNE), University of Bonn - Institute of Innate Immunity, University of Bonn - Institute of Innate Immunity, University of Bonn - Institute of Innate Immunity, Karolinska Institutet - Computational Medicine Unit, Universidad Pública de Navarra - Translational Bioinformatics Unit, King Abdullah University of Science and Technology (KAUST) - Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology (KAUST) - Biological and Environmental Science and Engineering Division, Technology University of Braunschweig - Department of Bioinformatics and Biochemistry, German Center for Neurodegenerative Diseases (DZNE) and University of Bonn - Institute of Innate Immunity
Downloads 174 (435,504)
Citation 6

Abstract:

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Microglia, Alzheimer's disease, NLRP3, inflammasome, glutaminolysis, α-ketoglutarate, phagocytosis, amyloid-β

2.

Trem2 Signaling Exploits Combinatorial Binding of MITF/TFE and ATF/AP-1 Transcription Factors to Drive Disease-Responsive Microglia Phenotypes

Number of pages: 102 Posted: 08 Jul 2026
University of California, San Diego (UCSD) - Department of Cellular and Molecular Medicine, affiliation not provided to SSRN, affiliation not provided to SSRN, University of California, San Diego (UCSD) - Department of Cellular and Molecular Medicine, affiliation not provided to SSRN, affiliation not provided to SSRN, Tongji University, German Center for Neurodegenerative Diseases (DZNE), Yale University, Whitehead Institute for Biomedical Research, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Massachusetts Institute of Technology and Harvard University - Broad Institute, Broad Institute of Harvard and MIT - Stanley Center for Psychiatric Research, Banner Health - Civin Laboratory for Neuropathology, Banner Health - Civin Laboratory for Neuropathology, University of Bonn - Institute of Innate Immunity, affiliation not provided to SSRN, affiliation not provided to SSRN, University of California, San Diego (UCSD), affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Imperial College London, affiliation not provided to SSRN and University of California, San Diego (UCSD) - Department of Cellular and Molecular Medicine
Downloads 21

Abstract:

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Microglia, Alzheimer's Disease, Amyloid, Epigenetics, Enhancer, Transcriptional Regulation, TREM2, MITF/TFE and AP-1 Transcription Factor Families, Xenotransplantation, Sterile Model of Inflammation, Disease Associated Microglia