Shandong First Medical University - Department of Endocrinology and Metabolism, Shandong First Medical University, Shandong First Medical University - Department of Endocrinology and Metabolism, Shandong First Medical University, Shandong University - Department of Biostatistics, Shanghai Jiao Tong University (SJTU) - Institute and Department of Endocrinology and Metabolism, Shandong First Medical University, Shandong First Medical University, Shandong First Medical University - Department of Endocrinology and Metabolism, Capital Medical University - Department of Epidemiology and Health Statistics, Shandong University, Shandong First Medical University - Department of Endocrinology, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Department of Endocrinology and Shandong First Medical University - Science and Technology Innovation Center