Universidade do Estado do Amazonas - Escola Superior de Ciências da Saúde, Universidade do Estado do Amazonas - Escola Superior de Ciências da Saúde, University of São Paulo (USP) - Faculdade de Ciências Farmacêuticas, Universidade do Estado do Amazonas - Escola Superior de Ciências da Saúde, Georgia Institute of Technology - Center for Operations Research in Medicine and Healthcare, Georgia Institute of Technology - Center for Operations Research in Medicine and Healthcare, University of São Paulo (USP) - Faculdade de Ciências Farmacêuticas, University of São Paulo (USP) - Department of Electronic Systems Engineering, University of São Paulo (USP) - Instituto de Medicinal Tropical, University of São Paulo (USP) - LIM-46 e LIM-49 do Instituto de Medicina Tropical, University of Amazonas State - Graduate Program in Tropical Medicine, University of Amazonas State - Graduate Program in Tropical Medicine and University of São Paulo (USP) - Department of Clinical and Toxicological Analyses