default author photo

Laurent R. Chiarelli

University of Pavia

Corso Strada Nuova, 65

27100 Pavia, 27100

Italy

  • University of Pavia

SCHOLARLY PAPERS

3

DOWNLOADS

126

TOTAL CITATIONS

0

Scholarly Papers (3)

Actions:
Email selected abstracts
1.

SELECTIVE VULNERABILITY OF HNE INHIBITION TO OXIDATIVE STRESS: A COMPARATIVE STUDY OF ALVELESTAT AND SIVELESTAT

Number of pages: 33 Posted: 29 Sep 2025
Maura D'Amato, Pasquale Linciano, Laurent R. Chiarelli, Angelica Pellegrini, Giampiero Pietrocola, Paolo Iadarola, Simona Collina and Simona Viglio
affiliation not provided to SSRN, University of Pavia, University of Pavia, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Pavia and affiliation not provided to SSRN
Downloads 45 (1,121,190)

Abstract:

Loading...

human neutrophil elastase (HNE), α1-antitrypsin (AAT), alvelestat, sivelestat, HNE inhibitors, chronic lung diseases

2.

Benzothiozinone Derivatives with Anti-Tubercular Activity−Further Side Chain Investigation

Number of pages: 23 Posted: 14 Nov 2023
Xiaomei Wu, Wenxin Wang, Giovanni Stelitano, Olga Ryabova, Bin Wang, Wei Niu, Mario Cocorullo, Rui Shi, Laurent R. Chiarelli, Vadim Makarov, Yu Lu, Chuan Li and chunhua qiao
Soochow University, Nanjing University of Chinese Medicine (NJUCM), University of Pavia, Russian Academy of Sciences (RAS) - Research Center of Biotechnology, Capital Medical University - Beijing Chest Hospital, Chinese Academy of Sciences (CAS) - Shanghai Institute of Materia Medica, University of Pavia, Soochow University, University of Pavia, Russian Academy of Sciences (RAS) - Research Center of Biotechnology, Capital Medical University - Beijing Chest Hospital, Nanjing University of Chinese Medicine (NJUCM) and Soochow University - College of Pharmaceutical Sciences
Downloads 43 (1,170,409)

Abstract:

Loading...

anti-tubercular activity, DprE1 inhibitor, benzothiazinone derivatives, structure activity relationship

3.

Side Chain-Modified Benzothiazinone Derivatives with Anti-Mycobacterial Activity

Number of pages: 31 Posted: 01 Dec 2022
Dongguang Fan, Bin Wang, Giovanni Stelitano, Karin Savková, Olga Ryabova, Rui Shi, Xiaomei Wu, Katarína Mikušová, Vadim Makarov, Laurent R. Chiarelli, Yu Lu, Yuzhi Hong and chunhua qiao
Soochow University, Capital Medical University - Beijing Chest Hospital, University of Pavia, Comenius University, Russian Academy of Sciences (RAS) - Research Center of Biotechnology, Soochow University, Soochow University, Comenius University, Russian Academy of Sciences (RAS) - Research Center of Biotechnology, University of Pavia, Capital Medical University - Beijing Chest Hospital, Soochow University and Soochow University - College of Pharmaceutical Sciences
Downloads 38 (1,222,651)

Abstract:

Loading...

Anti-tubercular agents, DprE1 inhibitor, Benzothiazinone analogs, Structure activity relationship, in vivo activity