University College London - Institute of Ophthalmology, University of London - Population Health Research Institute, Homerton Healthcare NHS Foundation Trust, Government of the United Kingdom - Moorfields Eye Hospital, Homerton Healthcare NHS Foundation Trust, Homerton Healthcare NHS Foundation Trust, University of Washington - Department of Ophthalmology, Kingston University - School of Computer Science and Mathematics, Kingston University - School of Computer Science and Mathematics, Kingston University - School of Computer Science and Mathematics, University of Durham - Department of Computer Science, National Institutes of Health, Bethesda - Division of Epidemiology and Clinical Applications, National Eye Institute, Ophthalmic Research Consultants, Institute of Cancer Research (ICR) - Division of Genetics and Epidemiology, University College London - Institute of Health Informatics, University of Washington - Department of Ophthalmology, University College London - Institute of Ophthalmology, University College London - Institute of Ophthalmology and University of London - Population Health Research Institute