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Claudiu T. Supuran

University of Florence

Piazza di San Marco, 4

Florence, 50121

Italy

  • University of Florence

SCHOLARLY PAPERS

8

DOWNLOADS

439

TOTAL CITATIONS

1

Scholarly Papers (8)

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1.

Discover the Power of Lithospermic Acid as Human Carbonic Anhydrase Va and Pancreatic Lipase Inhibitor Through in Silico and in Vitro Studies

Number of pages: 20 Posted: 27 Mar 2024
Emanuele Liborio Citriniti, Roberta Rocca, Giosuè Costa, Claudia Sciacca, Nunzio Cardullo, Vera Muccilli, Anastasia Karioti, fabrizio carta, Claudiu T. Supuran, Stefano Alcaro and Francesco Ortuso
affiliation not provided to SSRN, affiliation not provided to SSRN, Magna Graecia University of Catanzaro, Università degli Studi di Catania, University of Catania, University of Catania, Aristotle University of Thessaloniki, University of Florence, University of Florence, Magna Graecia University of Catanzaro and Magna Graecia University of Catanzaro
Downloads 83 (790,029)

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carbonic anhydrase, pancreatic lipase, Docking, obesity, lithospermic acid

2.

Design, Anticancer Activity, and Mechanistic Evaluation of a Novel Class of Selective Human Carbonic Anhydrase IX Inhibitors Featuring a Trifluorodihydroxypropanone Pharmacophore

Number of pages: 41 Posted: 30 Jun 2025
Nicolino Pala, Federico Ladu, Wojciech Szlasa, Roberta Cadoni, Carrie Lomelino, Brian P. Mahon, Mitchell Gulkis, Robert McKenna, Alessandro Dessì, Roberto N. Dallocchio, Antonio Demelas, Mauro Parma, Dominga Rogolino, Claudia Crosio, Ciro Iaccarino, Julita Kulbacka, Daniela Vullo, fabrizio carta, Claudiu T. Supuran and Mario Sechi
affiliation not provided to SSRN, affiliation not provided to SSRN, Wroclaw Medical University, affiliation not provided to SSRN, University of Florida, University of Florida, University of Florida, University of Florida, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Parma, University of Parma, Università degli Studi di Sassari - Department of Biomedical Sciences, affiliation not provided to SSRN, Wroclaw Medical University, University of Florence, University of Florence, University of Florence and affiliation not provided to SSRN
Downloads 75 (852,604)

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Carbonic Anydrases, hCA IX isoform, trifluorodihydroxypropanones, Anticancer agents, X-ray co-crystals

3.

Development of Novel Organometallic Sulfonamides with N-Ethyl or N-Methyl Benzenesulfonamide Units as Potential Human Carbonic Anhydrase I, Ii, Ix and Xii Isoforms’ Inhibitors: Synthesis, Biological Evaluation and Docking Studies

Number of pages: 26 Posted: 07 May 2024
Miguel Gallardo, Rodrigo Arancibia González, Claudiu T. Supuran, Alessio Nocentini, David Villaman, Patricia M. Toro, Michelle Muñoz-Osses and Carolina Mascayano
Universidad de Concepción, Universidad de Concepción, University of Florence, University of Florence, Universidad de Concepción, affiliation not provided to SSRN, affiliation not provided to SSRN and affiliation not provided to SSRN
Downloads 60 (989,921)

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Bioorganometallics, synthesis, Characterization, Carbonic anhydrase inhibitors, docking

4.

Synthesis and molecular docking of novel hybrid 1,2,4-triazole/1,3,4-oxadiazole benzenesulfonamides as isoform-selective carbonic anhydrase inhibitors

Number of pages: 40 Posted: 04 Dec 2025
Olcay Bekircan, Sila Can Osmanogullari, Simone Giovanuzzi, Claudiu T. Supuran and Ugur Uzuner
Karadeniz Technical University, Karadeniz Technical University, University of Florence, University of Florence and Karadeniz Technical University
Downloads 53 (1,074,648)

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1, 2, 4-triazoles, 1, 3, 4-oxadiazoles, sulfonamides, carbonic anhydrase, isoform selective CA inhibitors, Molecular docking

5.

4-Cyanamido-Substituted Benzenesulfonamides Act as Dual Carbonic Anhydrase and Cathepsin Inhibitors

Number of pages: 7 Posted: 07 Jun 2023
Morteza Abdoli, Vesa Krasniqi, Alessandro Bonardi, Claudiu T. Supuran, Raivis Žalubovskis and Michael Guetschow
Riga Technical University, University Bonn, University of Florence, University of Florence, Riga Technical University and University Bonn
Downloads 46 (1,109,210)
Citation 1

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Carbonic anhydrases, cathepsins, sulfonamides, cyanamides

6.

Hitting Two Birds with One Stone: Dual Modulation of Brain Carbonic Anhydrases and Histone Deacetylases Boosts Memory Consolidation

Number of pages: 45 Posted: 11 Mar 2025
Alessia Costa, Murat Bozdag, Gioele Renzi, Barbara Rani, Maria Beatrice Passani, Andrea Angeli, fabrizio carta, Gustavo Provensi and Claudiu T. Supuran
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Florence, University of Florence, affiliation not provided to SSRN and University of Florence
Downloads 44 (1,133,231)

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cognition, D-phenylalanine, multitarget ligands, Carbonic Anhydrase activators, Histone Deacetylase inhibitors, metalloenzymes

7.

Novel carbonic anhydrase inhibitors, 4-alkylthio-2-chloro-5-[(2-arylmethylidene)hydrazinecarbonyl]benzenesulfonamides, induce MAPK/ERK-mediated cell cycle arrest and mitochondrial associated-apoptosis in MCF-7 breast cancer cells

Number of pages: 41 Posted: 24 Jul 2024
Beata Żołnowska, Jarosław Sławiński, Jarosław Chojnacki, Andrea Petreni, Claudiu T. Supuran and Anna Kawiak
Medical University of Gdańsk, affiliation not provided to SSRN, Gdańsk University of Technology, University of Florence, University of Florence and affiliation not provided to SSRN
Downloads 39 (1,209,354)

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Benzenesulfonamide, synthesis, Anticancer, Apoptosis, Carbonic anhydrase, MAPK/ERK pathway, Cell cycle arrest

8.

Comparative Co2 and Sio2 Hydratase Activity of an Enzyme from the Siliceous Demosponge Suberites Domuncula

Number of pages: 28 Posted: 13 May 2024
Andrea Angeli, Viviana De Luca, Clemente Capasso, Luigi F. Di Costanzo and Claudiu T. Supuran
University of Florence, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Naples Federico II and University of Florence
Downloads 39 (1,196,171)

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Silicase, Silica Degradation, Carbonic Anhydrase, Versatile Catalytic Action