affiliation not provided to SSRN, affiliation not provided to SSRN, Wroclaw Medical University, affiliation not provided to SSRN, University of Florida, University of Florida, University of Florida, University of Florida, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Parma, University of Parma, Università degli Studi di Sassari - Department of Biomedical Sciences, affiliation not provided to SSRN, Wroclaw Medical University, University of Florence, University of Florence, University of Florence and affiliation not provided to SSRN