University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham - Institute of Metabolism and Systems Research, University of Lille II - U1190-EGID, University of Lille II - U1190-EGID, University of Lille II - U1190-EGID, Università Vita-Salute San Raffaele - San Raffaele Diabetes Research Institute, Università Vita-Salute San Raffaele - San Raffaele Diabetes Research Institute, University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham - Institute of Metabolism and Systems Research, University of Oxford - Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford - Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford - Oxford Centre for Diabetes, Endocrinology and Metabolism, Imperial College London - Section of Cell Biology and Functional Genomics, University of Montreal - Faculty of Medicine, University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham - Institute of Metabolism and Systems Research and University of Birmingham - Institute of Metabolism and Systems Research