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Xiamen University - Department of Rheumatology and Clinical Immunology, Xiamen University - School of Medicine, Xiamen University - School of Medicine, Xiamen University - Department of Rheumatology and Clinical Immunology, Xiamen University - School of Medicine, Xiamen University - Department of Rheumatology and Clinical Immunology, Xiamen University - Department of Rheumatology and Clinical Immunology, Xiamen University - Department of Rheumatology and Clinical Immunology and Xiamen University - Department of Rheumatology and Clinical Immunology