Xiamen University - Department of Rheumatology and Clinical Immunology, Xiamen University - School of Medicine, Xiamen University - School of Medicine, Xiamen University - Department of Rheumatology and Clinical Immunology, Xiamen University - School of Medicine, Xiamen University - Department of Rheumatology and Clinical Immunology, Xiamen University - Department of Rheumatology and Clinical Immunology, Xiamen University - Department of Rheumatology and Clinical Immunology and Xiamen University - Department of Rheumatology and Clinical Immunology