default author photo

Jean-Louis Mergny

École Polytechnique, Paris

SCHOLARLY PAPERS

3

DOWNLOADS

109

TOTAL CITATIONS

0

Scholarly Papers (3)

Actions:
Email selected abstracts
1.

Design, Synthesis, Biophysical and Biological Evaluation of Original Condensed Pyrrolopyrimidine and Pyrrolopyridine Ligands as Anti-Sars-Cov-2 Agents Targeting G4

Number of pages: 57 Posted: 04 Mar 2025
Jean Guillon, Solène Savrimoutou, Nicolas Da Rocha, Sandra Albenque-Rubio, Olivier Helynck, Cyrielle Durand, Jeanne Chiaravalli, Noël Pinaud, Luisa Ronga, Stéphane Moreau, Simon Chirold, Tshering Zangmo, Lindita Lari, Melika Arab, Jean-Louis Mergny, Hélène Munier-Lehmann and Marc Lavigne
affiliation not provided to SSRN, affiliation not provided to SSRN, University of Paris-Saclay - Institut Pasteur, affiliation not provided to SSRN, University of Paris-Saclay - Institut Pasteur, University of Paris-Saclay - Institut Pasteur, University of Paris-Saclay - Institut Pasteur, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, École Polytechnique, Paris, University of Paris-Saclay - Institut Pasteur and University of Paris-Saclay - Institut Pasteur
Downloads 55 (1,010,164)

Abstract:

Loading...

Guanine quadruplex, G4 ligands, SARS-CoV-2, Nsp3, COVID-19, Antiviral molecule, Pyrrolopyrimidine, Pyrrolopyridine, FRET-melting, HTRF.

2.

DNA G‑Quadruplexes in the Genome of Trypanosoma Cruzi as Potential Therapeutic Targets for Chagas Disease: Dithienylethene Ligands as Effective Antiparasitic Agents

Number of pages: 40 Posted: 27 May 2024
Manuel Pérez-Soto, Javier Ramos-Soriano, Pablo Peñalver, Efres Belmonte-Reche, Michael O'Hagan, Anne Cucchiarini, Jean-Louis Mergny, Carmen Galán, Manuel Carlos López, Carmen Thomas and Juan Carlos Morales
affiliation not provided to SSRN, University of Bristol, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Bristol, École Polytechnique, Paris, École Polytechnique, Paris, University of Bristol, Spanish National Research Council (CSIC), Spanish National Research Council (CSIC) and affiliation not provided to SSRN
Downloads 27 (1,372,601)

Abstract:

Loading...

Trypanosome cruzi, Chagas disease, DNA G-quadruplex, therapeutic target, ligand, drug

3.

N-Methyl Mesoporphyrin Ix (Nmm) as Electrochemical Probe for Detection of Guanine Quadruplexes

Number of pages: 23 Posted: 08 May 2023
Daniel Dobrovodsky, Ales Danhel, Daniel Renciuk, Jean-Louis Mergny and Miroslav Fojta
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, École Polytechnique, Paris and affiliation not provided to SSRN
Downloads 27 (1,359,097)

Abstract:

Loading...

N-methyl mesoporphyrin IX, G-quadruplex, Electrochemical probe, Adsorption, Electrochemistry, DNA