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Manuel Carlos López

Spanish National Research Council (CSIC)

Serrano, 117

Madrid, 28006

Spain

  • Spanish National Research Council (CSIC)

SCHOLARLY PAPERS

2

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101

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0

Scholarly Papers (2)

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1.

Safety of Alternative Benznidazole and Nifurtimox Regimens for Adults with Chronic Trypanosoma Cruzi Infection (TESEO): An Open-Label, Randomised, Non-Inferiority Phase 2 Trial

Number of pages: 17 Posted: 02 Mar 2026
Cristina Alonso-Vega, Jimy José Pinto, Gimena Rojas, Wilson García, Alejandro Palacios, Susana Méndez, Virginia R. González, Mónica Laserna, Isabela Ribeiro, María Jesús Pinazo delgado, Carmen Thomas, Manuel Carlos López, Irene Losada, Lourdes Ortiz, Julio Urbina, Sergi Sanz, Joaquim Gascon, Faustino Torrico, Igor Almeida and TESEO Study Group
Barcelona Institute for Global Health (ISGlobal), Fundación Ciencia y Estudios Aplicados para el Desarrollo en Salud y Medio Ambiente (CEADES), Fundación Ciencia y Estudios Aplicados para el Desarrollo en Salud y Medio Ambiente (CEADES), Fundación Ciencia y Estudios Aplicados para el Desarrollo en Salud y Medio Ambiente (CEADES), Fundación Ciencia y Estudios Aplicados para el Desarrollo en Salud y Medio Ambiente (CEADES), Barcelona Institute for Global Health (ISGlobal), University of Texas at El Paso, Fundación Ciencia y Estudios Aplicados para el Desarrollo en Salud y Medio Ambiente (CEADES), Drugs for Neglected Diseases Initiative (DNDi), Barcelona Institute for Global Health (ISGlobal), Spanish National Research Council (CSIC), Spanish National Research Council (CSIC), Barcelona Institute for Global Health (ISGlobal), Fundación Ciencia y Estudios Aplicados para el Desarrollo en Salud y Medio Ambiente (CEADES), Venezuelan Institute for Scientific Research, Barcelona Institute for Global Health (ISGlobal), Barcelona Institute for Global Health (ISGlobal), Fundación Ciencia y Estudios Aplicados para el Desarrollo en Salud y Medio Ambiente (CEADES), University of Texas at El Paso and Independent
Downloads 74 (875,328)

Abstract:

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Chagas disease, Chemotherapy, Benznidazole (BZN), Nifurtimox (NFX), Drug-related adverse events (DRAEs)

2.

DNA G‑Quadruplexes in the Genome of Trypanosoma Cruzi as Potential Therapeutic Targets for Chagas Disease: Dithienylethene Ligands as Effective Antiparasitic Agents

Number of pages: 40 Posted: 27 May 2024
Manuel Pérez-Soto, Javier Ramos-Soriano, Pablo Peñalver, Efres Belmonte-Reche, Michael O'Hagan, Anne Cucchiarini, Jean-Louis Mergny, Carmen Galán, Manuel Carlos López, Carmen Thomas and Juan Carlos Morales
affiliation not provided to SSRN, University of Bristol, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Bristol, École Polytechnique, Paris, École Polytechnique, Paris, University of Bristol, Spanish National Research Council (CSIC), Spanish National Research Council (CSIC) and affiliation not provided to SSRN
Downloads 27 (1,372,601)

Abstract:

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Trypanosome cruzi, Chagas disease, DNA G-quadruplex, therapeutic target, ligand, drug