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Álvaro Lorente-Macías

affiliation not provided to SSRN

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Scholarly Papers (1)

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Exploring Trisubstituted Adenine Derivatives as Adenosine A1 Receptor Ligands with Antagonist Activity: Synthesis, Biological Evaluation and Molecular Modelling

Number of pages: 50 Posted: 06 Feb 2025
Laura B. Córdoba-Gómez, Álvaro Lorente-Macías, María Isabel Loza, José Brea, Antón Leandro Martínez, Jonathon Mok, Ben King, Francisco Franco-Montalban, Antonio González García, Juan Jose Guardia-Monteagudo, Maria Matos, Asier Unciti-Broceta, Juan Jose Diaz-Mochon and María J. Pineda de las Infantas
University of Granada, affiliation not provided to SSRN, Universidade de Santiago de Compostela, Universidade de Santiago de Compostela, Universidade de Santiago de Compostela, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Granada - Campus La Cartuja, affiliation not provided to SSRN, S.L. Parque Tecnológico de la Salud, Universidade de Santiago de Compostela, affiliation not provided to SSRN, S.L. Parque Tecnológico de la Salud and University of Granada
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Abstract:

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Adenine scaffold, docking simulation, cancer cell lines, antiproliferation, orthosteric binding site, selectivity index, pharmacokinetic properties