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Steven De Jonghe

KU Leuven

SCHOLARLY PAPERS

6

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293

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0

Scholarly Papers (6)

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1.

Antiviral Evaluation of Phenylalanine Derivatives Carrying Carboxylic Acid Bioisosteres: Design, Synthesis, Molecular Modelling and Antiviral Activity

Number of pages: 23 Posted: 18 Jun 2025
Merve CAMCI, Görkem Güngör, Steven De Jonghe, Dirk Jochmans, Mehmet Özbil, Johan Neyts, Suzanne J. F. Kaptein, Halil Şenol, Aytekin Köse, Nilgün Karalı and Mikail Gezginci
Istanbul University, Gebze Technical University, KU Leuven, Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Gebze Technical University, KU Leuven - Laboratory of Virology and Chemotherapy, KU Leuven, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN and affiliation not provided to SSRN
Downloads 64 (924,743)

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phenylalanine, bioisostere, Antiviral, Molecular docking, molecular dynamics

2.

Steroidal 21-Imidazolium Salt Derivatives: Synthesis and Antitumoral Activity

Number of pages: 28 Posted: 17 May 2024
Natalia Sucman, Dmitri Ya. Bilan, Sergiu Cojocari, Vsevolod Pogrebnoi, Eugenia Stîngaci, Vladimir Khripach, Vladimir Zhabinskii, Tatsiana Tsybruk, Irina Grabovec, Olesya Panibrat, Sergiu Shova, Leentje Persoons, Dominique Schols, Steven De Jonghe and Fliur Zainutdin MACAEV
Moldova State University, Moldova State University, Moldova State University, Moldova State University, Moldova State University, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Romanian Academy, KU Leuven, KU Leuven, KU Leuven and Moldova State University
Downloads 55 (1,010,164)

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imidazolium salts, Prostate cancer, CYP17A1.

3.

Benzothiazole-Acetamide Hybrids as Anti-Proliferative Agents: Synthesis, Docking, and Biological Evaluation

Number of pages: 31 Posted: 19 Dec 2025
Mahnoor Imtiaz, Leentje Persoons, Dirk Daelemans, Steven De Jonghe and Shahid Hameed
affiliation not provided to SSRN, KU Leuven, Rega Institute for Medical Research - KU Leuven Department of Microbiology, Immunology and Transplantation, KU Leuven and Quaid-i-Azam University
Downloads 48 (1,121,190)

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Aza-heterocycles, Benzothiazoles, Acetamides, Anti-proliferative activity, Computational analysis

4.

Structure-Activity Relationship Study of Navarixin Analogues as Dual Cxcr2 and Ccr7 Antagonists

Number of pages: 51 Posted: 18 Nov 2024
Anže Meden, Sandra Claes, Tom Van Loy, Maša Zorman, Matic Proj, Dominique Schols, Stanislav Gobec and Steven De Jonghe
University of Ljubljana, KU Leuven, KU Leuven, University of Ljubljana, University of Ljubljana, KU Leuven, University of Ljubljana and KU Leuven
Downloads 46 (1,109,210)

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CCR7, CXCR2, antagonist, navarixin, 1, 2, 5-thiazole 1, 1-dioxide

5.

Biomimetic Semi-synthesis, Structural Optimization and anti-HIV Activity of Naturally Scarce Eupholathone-, Lathyranone- and Integerrimine-type Euphorbia Diterpenoids

Number of pages: 18 Posted: 20 Oct 2025
Wei Cheng, Peng Wen, Pei-Yin Song, Yang Zhang, Jin-Bu Xu, Steven De Jonghe, Dominique Schols and Feng Gao
Southwest Jiaotong University, Southwest Jiaotong University, Southwest Jiaotong University, KU Leuven, Southwest Jiaotong University, KU Leuven, KU Leuven and Southwest Jiaotong University - Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs
Downloads 44 (1,133,231)

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Euphorbia diterpenoids, Eupholathones, Lathyranones, Integerrimenes, Anti-HIV activity

6.

Synthesis and Structure-Activity Relationship Study of Phenoxybenzylpiperazine Analogues as CCR8 Agonists

Number of pages: 45 Posted: 21 Jun 2023
Qifei Li, Sandra Claes, Yenthel Verhaegen, Stijn Anthonissen, Tom Van Loy, Dominique Schols, Wim Dehaen and Steven De Jonghe
KU Leuven, KU Leuven, KU Leuven, KU Leuven, KU Leuven, KU Leuven, KU Leuven and KU Leuven
Downloads 36 (1,249,711)

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CCR8, agonist, phenoxybenzylpiperazine