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Dominique Schols

KU Leuven

SCHOLARLY PAPERS

6

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418

TOTAL CITATIONS

0

Scholarly Papers (6)

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1.

Multi-Cohort Cross-Omics Analysis Reveals Disease Mechanisms and Therapeutic Targets in a Neglected Retroviral Neuroinflammatory Disorder

Number of pages: 30 Posted: 19 Feb 2025
Tatiane Assone, Isaac Racine, Soraya Maria Menezes, Fernanda de Toledo Gonçalves, Victor Angelo Folgosi, Rosa Maria do Nascimento Marcusso, Michel Elias Jung Haziot, Jerusa Smid, Flavia Esper Dahy, Maria Rita Polo Gascon, Arthur Maia Paiva, Bernardo Galvão-Castro, Maria Fernanda Grassi, Maísa Silva de Sousa, Marzia Puccioni-Sohler, Simone Kashima Haddad, Tim Dierckx, Jean-Claude Twizere, Edward L. Murphy, Roberta Bruhn, Sandra Claes, Evelien Vanderlinden, Dominique Schols, Jurgen Vercauteren, Carolina Alvarez, Giovanni Lopez, Michael Talledo, Eduardo Gotuzzo, Augusto César Penalva de Oliveira, Isabelle Cleynen, Jorge Casseb and Johan Van Weyenbergh
Universidade de São Paulo, KU Leuven, KU Leuven, Universidade de São Paulo, Universidade de São Paulo, Government of the Federative Republic of Brazil, Government of the Federative Republic of Brazil, Government of the Federative Republic of Brazil, Government of the Federative Republic of Brazil, Universidade de São Paulo, Universidade de São Paulo, Escola Bahiana de Medicina e Saúde Pública, affiliation not provided to SSRN, Federal University of Para, Rio de Janeiro State University, University of São Paulo (USP) - Ribeirão Preto Medical School, KU Leuven, University of Liège, University of California, San Francisco (UCSF), Vitalant Research Institute, KU Leuven, KU Leuven, KU Leuven, KU Leuven, Universidad Peruana Cayetano Heredia, Universidad Peruana Cayetano Heredia, Universidad Peruana Cayetano Heredia, Universidad Peruana Cayetano Heredia, Government of the Federative Republic of Brazil, KU Leuven, University of Sao Paulo (USP), Medical School, Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies and KU Leuven
Downloads 127 (572,948)

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neuroinflammation, retrovirus, neglected disease, multi-omics, ancestry

2.

Discovery and Exploration of Disubstituted [1,2,5]Oxadiazolo-[3,4-B]Pyrazines as Novel C-C Chemokine Receptor Type 5 Signaling Inhibitors Targeting the Intracellular Allosteric Binding Pocket

Number of pages: 57 Posted: 20 Dec 2024
Margaux Billen, Sten Reynders, Sandra Claes, Silke Kleinboelting, Jef Rozenski, Radu-George Bulai, Edoardo Rocca, Natalie Z M Homer, Scott P. Webster, Tim P. Kaminski, Eveline Lescrinier, Dominique Schols and Peter Verwilst
KU Leuven, KU Leuven, KU Leuven, affiliation not provided to SSRN, KU Leuven, KU Leuven, KU Leuven, Edinburgh Clinical Research Facility, affiliation not provided to SSRN, affiliation not provided to SSRN, KU Leuven, KU Leuven and KU Leuven
Downloads 106 (659,652)

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intracellular chemokine receptor antagonists, CCR5, SAR optimization, [1, 2, 5]oxadiazolo-[3, 4-b]pyrazines, binding mode validation

3.

Steroidal 21-Imidazolium Salt Derivatives: Synthesis and Antitumoral Activity

Number of pages: 28 Posted: 17 May 2024
Natalia Sucman, Dmitri Ya. Bilan, Sergiu Cojocari, Vsevolod Pogrebnoi, Eugenia Stîngaci, Vladimir Khripach, Vladimir Zhabinskii, Tatsiana Tsybruk, Irina Grabovec, Olesya Panibrat, Sergiu Shova, Leentje Persoons, Dominique Schols, Steven De Jonghe and Fliur Zainutdin MACAEV
Moldova State University, Moldova State University, Moldova State University, Moldova State University, Moldova State University, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Romanian Academy, KU Leuven, KU Leuven, KU Leuven and Moldova State University
Downloads 56 (1,010,164)

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imidazolium salts, Prostate cancer, CYP17A1.

4.

Structure-Activity Relationship Study of Navarixin Analogues as Dual Cxcr2 and Ccr7 Antagonists

Number of pages: 51 Posted: 18 Nov 2024
Anže Meden, Sandra Claes, Tom Van Loy, Maša Zorman, Matic Proj, Dominique Schols, Stanislav Gobec and Steven De Jonghe
University of Ljubljana, KU Leuven, KU Leuven, University of Ljubljana, University of Ljubljana, KU Leuven, University of Ljubljana and KU Leuven
Downloads 47 (1,109,210)

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CCR7, CXCR2, antagonist, navarixin, 1, 2, 5-thiazole 1, 1-dioxide

5.

Biomimetic Semi-synthesis, Structural Optimization and anti-HIV Activity of Naturally Scarce Eupholathone-, Lathyranone- and Integerrimine-type Euphorbia Diterpenoids

Number of pages: 18 Posted: 20 Oct 2025
Wei Cheng, Peng Wen, Pei-Yin Song, Yang Zhang, Jin-Bu Xu, Steven De Jonghe, Dominique Schols and Feng Gao
Southwest Jiaotong University, Southwest Jiaotong University, Southwest Jiaotong University, KU Leuven, Southwest Jiaotong University, KU Leuven, KU Leuven and Southwest Jiaotong University - Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs
Downloads 45 (1,133,231)

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Euphorbia diterpenoids, Eupholathones, Lathyranones, Integerrimenes, Anti-HIV activity

6.

Synthesis and Structure-Activity Relationship Study of Phenoxybenzylpiperazine Analogues as CCR8 Agonists

Number of pages: 45 Posted: 21 Jun 2023
Qifei Li, Sandra Claes, Yenthel Verhaegen, Stijn Anthonissen, Tom Van Loy, Dominique Schols, Wim Dehaen and Steven De Jonghe
KU Leuven, KU Leuven, KU Leuven, KU Leuven, KU Leuven, KU Leuven, KU Leuven and KU Leuven
Downloads 37 (1,249,711)

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CCR8, agonist, phenoxybenzylpiperazine