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Natalie Z M Homer

Edinburgh Clinical Research Facility

SCHOLARLY PAPERS

7

DOWNLOADS

366

TOTAL CITATIONS

1

Scholarly Papers (7)

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1.

Discovery and Exploration of Disubstituted [1,2,5]Oxadiazolo-[3,4-B]Pyrazines as Novel C-C Chemokine Receptor Type 5 Signaling Inhibitors Targeting the Intracellular Allosteric Binding Pocket

Number of pages: 57 Posted: 20 Dec 2024
Margaux Billen, Sten Reynders, Sandra Claes, Silke Kleinboelting, Jef Rozenski, Radu-George Bulai, Edoardo Rocca, Natalie Z M Homer, Scott P. Webster, Tim P. Kaminski, Eveline Lescrinier, Dominique Schols and Peter Verwilst
KU Leuven, KU Leuven, KU Leuven, affiliation not provided to SSRN, KU Leuven, KU Leuven, KU Leuven, Edinburgh Clinical Research Facility, affiliation not provided to SSRN, affiliation not provided to SSRN, KU Leuven, KU Leuven and KU Leuven
Downloads 106 (659,652)

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intracellular chemokine receptor antagonists, CCR5, SAR optimization, [1, 2, 5]oxadiazolo-[3, 4-b]pyrazines, binding mode validation

2.

Glucocorticoids, Oestrogens, Androgens, and 11-Oxygenated Androgens in Human Omental and Subcutaneous Adipose Tissue Before and after Sleeve Gastrectomy

Number of pages: 52 Posted: 26 Jul 2023
Sofia Laforest, Scott Denham, Alan Ramalho, Marie-Frédérique Gauthier, Nina Denver, Virginie Drolet-Labelle, Laurent Biertho, Natalie Z M Homer, Ruth Andrew and André Tchernof
University of Strathclyde, University of Nottingham - Queen's Medical Centre, Université Laval, Université Laval - Quebec Heart and Lung Institute, University of Strathclyde, Université Laval, Université Laval - Quebec Heart and Lung Institute, Edinburgh Clinical Research Facility, University of Strathclyde and Université Laval - Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec
Downloads 69 (891,180)

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steroid hormones, adipose tissue, adipocyte, bariatric surgery, weight loss, LC-MS/MS

3.

Development of a UPLC-MS/MS Method for the Simultaneous Analysis of AT7519 and Acetaminophen in a Mouse Model of Acute Inflammation

Number of pages: 12 Posted: 18 Apr 2022
Jennifer Ann Cartwright, Joanna P. Simpson, Natalie Z M Homer and Adriano G. Rossi
University of Edinburgh - Centre for Inflammation Research, University of Edinburgh, Edinburgh Clinical Research Facility and University of Edinburgh - Centre for Inflammation Research
Downloads 58 (989,921)

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Mass Spectrometry, Neutrophil, Hepatic, Paracetamol

4.

Thiosulfate Sulfurtransferase Deficiency Promotes Oxidative Distress and Aberrant NRF2 Function in the Brain

Number of pages: 23 Posted: 20 Oct 2023
Yang Luo, Laurent Chatre, Shaden Melhem, Zayana M. Al-Dahmani, Natalie Z M Homer, Anneke Miedema, Leo E. Deelman, Matthew Groves, Martin Feelisch, Nicholas M. Morton, Amalia Dolga and Harry van Goor
University of Groningen, Université de Caen-Normandie, University of Edinburgh, University of Groningen, Edinburgh Clinical Research Facility, University of Groningen - University Medical Center Groningen, University of Groningen, University of Groningen, University of Southampton, Nottingham Trent University, University of Groningen and University of Groningen - University Medical Center Groningen
Downloads 48 (1,097,529)

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Thiosulfate sulfurtransferase (TST), Reactive species, Antioxidant, Oxidative distress, Nrf2 signaling

5.

Primitive Steroidogenesis in Mast Cells: A Novel Regulatory Mechanism for Mast Cell Function

Number of pages: 36 Posted: 14 Feb 2025
Jhuma Pramanik, Qiuchen Zhao, Yumi Yamashita-Kanemaru, Hosni Hussein, Natalie Z M Homer, Soura Chakraborty, Sanu K. Shaji, Klaus Okkenhaug, Rahul Roychoudhuri, Bidesh Mahata and Sneak Peek Administrator
University of Cambridge, University of Cambridge, University of Cambridge, University of Cambridge, Edinburgh Clinical Research Facility, University of Cambridge, University of Cambridge, University of Cambridge, University of Cambridge, University of Cambridge and Independent
Downloads 38 (1,222,651)

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Mast cell, Steroidogenesis, Steroid-signalling, Pregnenolone, Degranulation, Regranulation, Immune & Tissue Homeostasis, Inflammation, Allergy.

6.

De Novo Steroidogenesis in Tumor Cells Drives Bone Metastasis and Osteoclastogenesis

Number of pages: 40 Posted: 01 Aug 2023
Joon B. Huh, Peter Benko, Luca F. Sandor, Toru Hiraga, Szilard Poliska, Csaba Dobo-Nagy, Joanna P. Simpson, Natalie Z M Homer, Bidesh Mahata, David S. Gyori and Sneak Peek Administrator
Semmelweis University, Semmelweis University, Semmelweis University, Matsumoto Dental University, University of Debrecen, Semmelweis University, University of Edinburgh, Edinburgh Clinical Research Facility, University of Cambridge, Semmelweis University and Independent
Downloads 28 (1,359,097)
Citation 1

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osteoclast, bone cancer, steroids

7.

Estrogenic profiles in lungs from a rat model of pulmonary arterial hypertension measured by liquid chromatography triple quadrupole mass spectrometry

Number of pages: 32 Posted: 26 May 2026
James W. Weatherill, Hicham Labazi, Nina Denver, Joanna P. Simpson, Scott Denham, Natalie Z M Homer, Margaret R. MacLean and Ruth Andrew
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Edinburgh, University of Nottingham - Queen's Medical Centre, Edinburgh Clinical Research Facility, affiliation not provided to SSRN and University of Strathclyde
Downloads 19 (1,541,665)

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estrogen, lung, liquid chromatography, mass spectrometry, rodent, pulmonary arterial hypertension