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Helena Mertlíková-Kaiserová

Czech Academy of Sciences - Institute of Organic Chemistry and Biochemistry

SCHOLARLY PAPERS

3

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116

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0

Scholarly Papers (3)

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1.

Discovery of a Potent and Selective Human AC2 Inhibitor Based on 7-Deazapurine Analogues of Adefovir

Number of pages: 47 Posted: 08 Aug 2023
Pavel Kraina, Michal Česnek, Eva Tloušťová, Helena Mertlíková-Kaiserová, Camryn J. Fulton, Emily K. Davidson, Val J. Watts and Zlatko Janeba
Czech Academy of Sciences - Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences - Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences - Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences - Institute of Organic Chemistry and Biochemistry, Purdue University, Purdue University, Purdue University and Czech Academy of Sciences - Institute of Organic Chemistry and Biochemistry
Downloads 49 (1,074,648)

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Acyclic nucleoside phosphonates, adefovir, 7-deazapurine, prodrugs, adenylate cyclase

2.

Design, Synthesis and Evaluation of Novel Thieno[2,3, d]Pyrimidine Derivatives as Potent and Specific RIPK2 Inhibitors

Number of pages: 12 Posted: 20 Oct 2023
Mbilo Misehe, Michal Šála, Marika Matoušová, Kamil Hercík, Hugo Kocek, Dominika Chalupská, Ema Chaloupecká, Miroslav Hájek, Evzen Boura, Helena Mertlíková-Kaiserová and Radim Nencka
Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences - Institute of Organic Chemistry and Biochemistry and Academy of Sciences of the Czech Republic - Institute of Organic Chemistry and Biochemistry
Downloads 37 (1,236,159)

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Kinase inhibitor, Thieno[2, 3d]pyrimidine derivative, Receptor-interacting protein kinase 2, RIPK2, NOD

3.

Fluorescence-Based Assay for Rapid Screening of Gabaa Receptor Modulating Steroid Antagonists (Gamsa)

Number of pages: 48 Posted: 25 Jul 2025
Jan Voldřich, Hana Zemková, Markéta Šmídková, Marika Matoušová, Eva Kudová and Helena Mertlíková-Kaiserová
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Czech Academy of Sciences, affiliation not provided to SSRN and Czech Academy of Sciences - Institute of Organic Chemistry and Biochemistry
Downloads 30 (1,332,057)

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High-throughput screening, neurosteroid, GABA, allopregnanolone, membrane potential, fluorescence-based assay