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Evzen Boura

Czech Academy of Sciences

SCHOLARLY PAPERS

2

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64

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Scholarly Papers (2)

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1.

Design, Synthesis and Evaluation of Novel Thieno[2,3, d]Pyrimidine Derivatives as Potent and Specific RIPK2 Inhibitors

Number of pages: 12 Posted: 20 Oct 2023
Mbilo Misehe, Michal Šála, Marika Matoušová, Kamil Hercík, Hugo Kocek, Dominika Chalupská, Ema Chaloupecká, Miroslav Hájek, Evzen Boura, Helena Mertlíková-Kaiserová and Radim Nencka
Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences, Czech Academy of Sciences - Institute of Organic Chemistry and Biochemistry and Academy of Sciences of the Czech Republic - Institute of Organic Chemistry and Biochemistry
Downloads 37 (1,236,159)

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Kinase inhibitor, Thieno[2, 3d]pyrimidine derivative, Receptor-interacting protein kinase 2, RIPK2, NOD

2.

Exploring Advanced Methodologies for NS5 Methyltransferase Targeted Drug Discovery

Number of pages: 26 Posted: 06 Sep 2025
Tomáš Otava, Matúš Drexler, Petra Krafčíková, Dominika Chalupská, Karel Chalupsky, Václav Veverka, Evzen Boura and Radim Nencka
Academy of Sciences of the Czech Republic - Institute of Organic Chemistry and Biochemistry, affiliation not provided to SSRN, affiliation not provided to SSRN, Czech Academy of Sciences, Academy of Sciences of the Czech Republic - Institute of Organic Chemistry and Biochemistry, affiliation not provided to SSRN, Czech Academy of Sciences and Academy of Sciences of the Czech Republic - Institute of Organic Chemistry and Biochemistry
Downloads 27 (1,359,097)

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Dengue virus NS5 methyltransferase, S-adenosylhomocysteine analogs, fluorescence polarization, NMR titration, Echo® mass spectrometry assay, X-ray crystallography, antiviral drug discovery, methyltransferase inhibitors