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Angela Genge

McGill University - Montreal Neurological Institute and Hospital

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Multimodal Digital Endpoints to Measure Disease Progression in An Amyotrophic Lateral Sclerosis Proof-Of-Concept Therapeutic Clinical Trial

Number of pages: 53 Posted: 06 Jul 2026
Diego Cadavid, Ines Hoffmann, Anil Tarachandani, Robert Scannevin, Brian Shook, Tara Haley, Shane Raines, Philip Van Damme, Pentti Tienari, Eino Solje, Manu Jokela, Angela Genge, Colleen O'Connell, Michael Neumann, Hardik Kothare, Vikram Ramanarayanan, Rumen Hristov, Pranav Krishna, Rachel Levy, Hariharan Rahul, Shichao Yue, Dina Katabi, Ruben van Eijk and Leonard van den Berg
Verge Genomics, Verge Genomics, Verge Genomics, Verge Genomics, Verge Genomics, Verge Genomics, 2b Analytics, KU Leuven - University Hospitals Leuven, University of Helsinki - Department of Neurology, University of Eastern Finland - Institute of Clinical Medicine, University of Turku - Turku University Hospital, McGill University - Montreal Neurological Institute and Hospital, International Spinal Cord Society (ISCoS), Modality.AI, Modality.AI, Modality.AI, Emerald Innovations, Emerald Innovations, Emerald Innovations, Emerald Innovations, Emerald Innovations, Emerald Innovations, Utrecht University - Department of Neurology and Neurosurgery and Utrecht University - Department of Neurology
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Abstract:

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ALS, clinical trial, PIKfyve, digital endpoints, accelerometry, touchless sensors, mobility, speech, breathing, sleep, neurofilament