University of Sheffield, University of Sheffield, Trinity College (Dublin) - Academic Unit of Neurology, Trinity College (Dublin) - Academic Unit of Neurology, Weizmann Institute of Science - Department of Molecular Genetics, Weizmann Institute of Science, Weizmann Institute of Science, University of Sheffield, University of Sheffield, University of Sheffield, University of Sheffield, University of Sheffield, University of Sheffield, University Medical Center Utrecht - Department of Neurology, University of Florida, King’s College London - Department of Basic and Clinical Neuroscience, King’s College London - Department of Basic and Clinical Neuroscience, Stanford University - Genetics Department, University of Sheffield, University of Turin, University College London, University of Rostock, Karolinska Institutet - Karolinska University Hospital, University of Valencia, Utrecht University - Department of Neurology, Bellvitge University Hospital, KU Leuven - University Hospitals Leuven, CHRU Tours, University of Lisbon, King’s College London - Department of Basic and Clinical Neuroscience, Weizmann Institute of Science - Department of Molecular Genetics, Lund University - Department of Biology, University of Sheffield - Sheffield Institute for Translational Neuroscience (SITraN), Trinity College (Dublin) - Academic Unit of Neurology, University of Sheffield and University of Sheffield - Sheffield Institute for Translational Neuroscience (SITraN)

Government of the United States of America - Neuromuscular Diseases Research Section, University of Sheffield, Government of the United States of America - Neuromuscular Diseases Research Section, University of Sheffield, St. Joseph's Hospital and Medical Center - Barrow Neurological Institute, National Institutes of Health, St. Joseph's Hospital and Medical Center - Barrow Neurological Institute, St. Joseph's Hospital and Medical Center - Barrow Neurological Institute, Government of the United States of America - National Institute on Aging (NIA), National Institute on Aging (NIA) - Computational Biology Group, King’s College London, National Institute on Aging - Neuromuscular Diseases Research Section, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’, University of Milan - IRCCS Istituto Auxologico Italiano, University of Piemonte Orientale, Utrecht University - University Medical Center (Utrecht), Utrecht University - Department of Neurology, Koc University, Koc University, National Institutes of Health, Government of the United States of America - National Institute on Aging (NIA), University of Turin, University of Milan, King’s College London - Department of Basic and Clinical Neuroscience, King’s College London, University of Milan - IRCCS Istituto Auxologico Italiano, University of Milan, University of Milan - IRCCS Istituto Auxologico Italiano, University of Piemonte Orientale, University Medical Center Utrecht - Department of Neurology, King’s College London - Department of Basic and Clinical Neuroscience, King’s College London, University of Padova, University of Brescia, University of Brescia, University of Brescia - Neurology Unit, IRCCS Mondino Foundation Pavia, Sapienza University of Rome, University of Ferrara, University of Turin, University of Turin, University of Turin, University of Turin, University of Turin, University of Turin, Università di Modena e Reggio Emilia, Istituti Clinici Scientifici Maugeri IRCCS, Istituti Clinici Scientifici Maugeri IRCCS, Agenzia Nazionale per i Servizi Sanitari Regionali - “S. Chiara” Hospital, University of Campania “Luigi Vanvitelli”, AV4 ASUR Marche, University of Turin, University of Turin, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Università degli Studi di Milano, Università degli Studi di Milano, University of Pavia, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’, University of Nottingham - NIHR Biomedical Research Centre, University of Nottingham - NIHR Biomedical Research Centre, University of Nottingham - NIHR Biomedical Research Centre, University of Nottingham - NIHR Biomedical Research Centre, Queen's University, University of Sheffield - Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield - Sheffield Institute for Translational Neuroscience (SITraN), King’s College London - Institute of Psychiatry, Psychology & Neuroscience (IoPPN), King’s College London - Department of Biostatistics & Health Informatics, Uniformed Services University of the Health Sciences - Department of Anatomy, Physiology and Genetics, Government of the United States of America - National Institute of Neurological Disorders and Stroke (NINDS), National Institute of Neurological Disorders and Stroke - Neurodegenerative Diseases Research Unit, King’s College London - Department of Basic and Clinical Neuroscience, Utrecht University - Department of Neurology, Trinity College (Dublin), Trinity College (Dublin) - Academic Unit of Neurology, University of Milan, University of Padova, University of Piemonte Orientale, UK-Dementia Research Institute at University College London, University of Edinburgh, University of Milan - IRCCS Istituto Auxologico Italiano, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’, National Institute of Neurological Disorders and Stroke - DIR Bioinformatics Section, Government of the United States of America - National Cancer Institute, National Institutes of Health, Bethesda - National Institute of Mental Health, National Institutes of Health, Bethesda - National Institute of Mental Health, National Institutes of Health, Bethesda - National Institute of Mental Health, University of Pisa, University of Milan, Koc University, Utrecht University - Department of Neurology, University of Montpellier, Emory University - Department of Neurology, University of Massachusetts Worcester - Department of Neurology, Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), King’s College London - Maurice Wohl Clinical Neuroscience Institute, University of Sheffield - Sheffield Institute for Translational Neuroscience (SITraN), Government of the United States of America - National Institute on Aging (NIA) and Government of the United States of America - Neuromuscular Diseases Research Section

National Institutes of Health, University of Sheffield, Government of the United States of America - Neuromuscular Diseases Research Section, University of Sheffield, St. Joseph's Hospital and Medical Center - Barrow Neurological Institute, National Institutes of Health, St. Joseph's Hospital and Medical Center - Barrow Neurological Institute, St. Joseph's Hospital and Medical Center - Barrow Neurological Institute, Government of the United States of America - National Institute on Aging (NIA), National Institute on Aging (NIA) - Computational Biology Group, King’s College London, National Institute on Aging - Neuromuscular Diseases Research Section, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’, University of Milan - IRCCS Istituto Auxologico Italiano, University of Piemonte Orientale, Utrecht University - University Medical Center (Utrecht), Utrecht University - Department of Neurology, Koc University, Koc University, National Institutes of Health, Government of the United States of America - National Institute on Aging (NIA), University of Turin, University of Milan, Utrecht University - University Medical Center (Utrecht), King’s College London - Department of Basic and Clinical Neuroscience, King’s College London, University of Milan - IRCCS Istituto Auxologico Italiano, University of Milan, University of Milan - IRCCS Istituto Auxologico Italiano, University of Piemonte Orientale, University Medical Center Utrecht - Department of Neurology, King’s College London - Department of Basic and Clinical Neuroscience, King’s College London, University of Padova, University of Brescia, University of Brescia, University of Brescia - Neurology Unit, IRCCS Mondino Foundation Pavia, Sapienza University of Rome, University of Ferrara, University of Turin, University of Turin, University of Turin, University of Turin, University of Turin, University of Turin, Università di Modena e Reggio Emilia, Istituti Clinici Scientifici Maugeri IRCCS, Istituti Clinici Scientifici Maugeri IRCCS, Agenzia Nazionale per i Servizi Sanitari Regionali - “S. Chiara” Hospital, University of Campania “Luigi Vanvitelli”, AV4 ASUR Marche, University of Turin, University of Turin, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Università degli Studi di Milano, Università degli Studi di Milano, University of Pavia, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’, University of Nottingham - NIHR Biomedical Research Centre, University of Nottingham - NIHR Biomedical Research Centre, University of Nottingham - NIHR Biomedical Research Centre, University of Nottingham - NIHR Biomedical Research Centre, Queen's University, University of Sheffield - Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield - Sheffield Institute for Translational Neuroscience (SITraN), King’s College London - Institute of Psychiatry, Psychology & Neuroscience (IoPPN), King’s College London - Department of Biostatistics & Health Informatics, Uniformed Services University of the Health Sciences - Department of Anatomy, Physiology and Genetics, Government of the United States of America - National Institute of Neurological Disorders and Stroke (NINDS), National Institute of Neurological Disorders and Stroke - Neurodegenerative Diseases Research Unit, King’s College London - Department of Basic and Clinical Neuroscience, Utrecht University - Department of Neurology, Trinity College (Dublin), Trinity College (Dublin) - Academic Unit of Neurology, University of Milan, University of Padova, University of Piemonte Orientale, UK-Dementia Research Institute at University College London, University of Edinburgh, University of Milan - IRCCS Istituto Auxologico Italiano, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’, National Institute of Neurological Disorders and Stroke - DIR Bioinformatics Section, Government of the United States of America - National Cancer Institute, National Institutes of Health, Bethesda - National Institute of Mental Health, National Institutes of Health, Bethesda - National Institute of Mental Health, National Institutes of Health, Bethesda - National Institute of Mental Health, University of Pisa, University of Milan, Koc University, Utrecht University - Department of Neurology, University of Montpellier, Emory University - Department of Neurology, University of Massachusetts Worcester - Department of Neurology, Government of the United States of America - National Institute on Aging (NIA), Barrow Neurological Institute, King’s College London - Maurice Wohl Clinical Neuroscience Institute, affiliation not provided to SSRN, Government of the United States of America - National Institute on Aging (NIA), Independent and Government of the United States of America - Neuromuscular Diseases Research Section

University of Queensland - Institute for Molecular Bioscience, University of Queensland - School Biomedical Science, Paris Descartes Université - Imagine Institute, University of Queensland - Queensland Brain Institute, University of Queensland - Institute for Molecular Bioscience, University of Queensland - Institute for Molecular Bioscience, University of California, Los Angeles (UCLA) - Department of Computer Science, University of Queensland - Institute for Molecular Bioscience, University of Queensland - Institute for Molecular Bioscience, University of Queensland - Institute for Molecular Bioscience, University of Melbourne - Florey Institute of Neuroscience and Mental Health, University of Melbourne - Florey Institute of Neuroscience and Mental Health, University of Queensland - Institute for Molecular Bioscience, Calvary Health Care Bethlehem - Department of Neurology, Royal Brisbane and Women's Hospital - Department of Neurology, Murdoch University - Fiona Stanley Hospital, Department of Neurology, Flinders Medical Centre - Department of Neurology, The University of Sydney - Brain and Mind Centre, Utrecht University - Department of Neurology, Utrecht University - Department of Neurology, Utrecht University - Department of Neurology, University of California, Los Angeles (UCLA) - Computer Science Department, Harvard University - Division of Population Sciences, University of California, San Francisco (UCSF) - Institute for Human Genetics, University of Queensland - Institute for Molecular Bioscience, Royal Brisbane and Women's Hospital - Department of Neurology, University of Queensland - Institute for Molecular Bioscience, University of Queensland - Queensland Brain Institute and University of Queensland - Institute for Molecular Bioscience