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Léa Mélin

University of Quebec at Montreal (UQAM)

Montreal

Canada

  • University of Quebec at Montreal (UQAM)

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Scholarly Papers (1)

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Development of Lm-41 and Af-2112, Two Flufenamic Acid-Derived Tead Inhibitors Obtained Through the Replacement of the Trifluoromethyl Group by Aryl Rings

Number of pages: 10 Posted: 15 Aug 2023
Ahmed Fnaiche, Léa Mélin, Narjara González Suárez, Victoria Vu, Fengling Li, Abdellah Allali-Hassani, Albina Bolotokova, Frédéric Allemand, Muriel Gelin, Philippe Cotelle, Simon Woo, Steven LaPlante, Dalia Barsyte, Vijayaratnam Santhakumar, Masoud Vedadi, Borhane Annabi, Jean-François Guichou and Alexandre Gagnon
University of Quebec at Montreal (UQAM), University of Quebec at Montreal (UQAM), University of Quebec at Montreal (UQAM), Goethe University Frankfurt - Structural Genomics Consortium, Goethe University Frankfurt - Structural Genomics Consortium, Goethe University Frankfurt - Structural Genomics Consortium, Goethe University Frankfurt - Structural Genomics Consortium, University of Montpellier, University of Montpellier, University of Lille, University of Quebec at Montreal (UQAM), University of Quebec at Montreal (UQAM), University of Toronto, Goethe University Frankfurt - Structural Genomics Consortium, Goethe University Frankfurt - Structural Genomics Consortium, Université du Québec à Montréal - Department of Chemistry, University of Montpellier and University of Quebec at Montreal (UQAM)
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Abstract:

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YAP-TEAD, Hippo pathway, transcription factors, Flufenamic acid, Niflumic acid