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Fengling Li

Goethe University Frankfurt - Structural Genomics Consortium

Grüneburgplatz 1

Frankfurt am Main, 60323

Germany

  • Goethe University Frankfurt - Structural Genomics Consortium

SCHOLARLY PAPERS

3

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186

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Scholarly Papers (3)

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1.

Development of Selective Class I Protein Arginine Methyltransferase Inhibitors Through Fragment-Based Drug Design Approach

Number of pages: 58 Posted: 28 Mar 2023
Debomita Bhattacharya, Alice Shi Ming Li, Barnali Paul, Uddipta Ghosh Dastidar, Vijayaratnam Santhakumar, Dipika Sarkar, Irene Chau, Fengling Li, Masoud Vedadi and Arindam Talukdar
Council of Scientific and Industrial Research (CSIR)- India - Indian Institute of Chemical Biology (CSIR-IICB), Goethe University Frankfurt - Structural Genomics Consortium, Council of Scientific and Industrial Research (CSIR)- India - Indian Institute of Chemical Biology (CSIR-IICB), Council of Scientific and Industrial Research (CSIR)- India - Indian Institute of Chemical Biology (CSIR-IICB), Goethe University Frankfurt - Structural Genomics Consortium, Council of Scientific and Industrial Research (CSIR)- India - Indian Institute of Chemical Biology (CSIR-IICB), Goethe University Frankfurt - Structural Genomics Consortium, Goethe University Frankfurt - Structural Genomics Consortium, Goethe University Frankfurt - Structural Genomics Consortium and Council of Scientific and Industrial Research (CSIR)- India - Indian Institute of Chemical Biology (CSIR-IICB)
Downloads 79 (816,709)

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PKMTs, PRMTs, Selective Inhibitors, Fragment-based Drug Design

2.

Development of Lm-41 and Af-2112, Two Flufenamic Acid-Derived Tead Inhibitors Obtained Through the Replacement of the Trifluoromethyl Group by Aryl Rings

Number of pages: 10 Posted: 15 Aug 2023
Ahmed Fnaiche, Léa Mélin, Narjara González Suárez, Victoria Vu, Fengling Li, Abdellah Allali-Hassani, Albina Bolotokova, Frédéric Allemand, Muriel Gelin, Philippe Cotelle, Simon Woo, Steven LaPlante, Dalia Barsyte, Vijayaratnam Santhakumar, Masoud Vedadi, Borhane Annabi, Jean-François Guichou and Alexandre Gagnon
University of Quebec at Montreal (UQAM), University of Quebec at Montreal (UQAM), University of Quebec at Montreal (UQAM), Goethe University Frankfurt - Structural Genomics Consortium, Goethe University Frankfurt - Structural Genomics Consortium, Goethe University Frankfurt - Structural Genomics Consortium, Goethe University Frankfurt - Structural Genomics Consortium, University of Montpellier, University of Montpellier, University of Lille, University of Quebec at Montreal (UQAM), University of Quebec at Montreal (UQAM), University of Toronto, Goethe University Frankfurt - Structural Genomics Consortium, Goethe University Frankfurt - Structural Genomics Consortium, Université du Québec à Montréal - Department of Chemistry, University of Montpellier and University of Quebec at Montreal (UQAM)
Downloads 67 (899,324)

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YAP-TEAD, Hippo pathway, transcription factors, Flufenamic acid, Niflumic acid

3.

Identification and optimization of first-in-class RNA helicase inhibitors

Number of pages: 33 Posted: 09 Jan 2026
Xiaowen Wang, Feijun Wang, Deyu Kong, Dilipkumar Uredi, Fengling Li, Feng Li, Jayachandra Rayadurgam, Hanxuan Li, Esther Wolf, U. Hang Chan, Irene Chau, Hong Zeng, Julia Garcia Perez, Derek J. Wilson, Frances M. Bashore, Xiaodong Wang, Levon Halabelian, Kevin J. Frankowski, Dmitri Kireev and Alison Donnelly Axtman
University of Missouri, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Goethe University Frankfurt - Structural Genomics Consortium, Nanjing University of Science and Technology, affiliation not provided to SSRN, affiliation not provided to SSRN, York University, University of Toronto, University of Toronto, University of Toronto, University of Toronto, York University, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Toronto, affiliation not provided to SSRN, University of Missouri - Columbia and University of North Carolina (UNC) at Chapel Hill - Structural Genomics Consortium
Downloads 40 (1,183,237)

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RNA helicases, MDA5, LGP2, DDX1, inhibitor, structure-based virtual screening, hit-to-lead optimization, HDX-MS