Author Page for Alison Donnelly Axtman

A Brain-Penetrant PIKfyve Inhibitor Reverses Experimental Neuropathic Pain via Inhibition of Sodium Channels

Number of pages: 21 Posted: 19 Apr 2024

Erick J. Rodriguez-Palma, Sophia M. Min, Aida Calderon-Rivera, Santiago Loya-Lopez, Rajesh Khanna and Alison Donnelly Axtman

University of Florida, University of North Carolina (UNC) at Chapel Hill - Structural Genomics Consortium, University of Florida, University of Florida, University of Florida and University of North Carolina (UNC) at Chapel Hill - Structural Genomics Consortium

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Abstract:

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Development of a Potent and Selective Chemical Probe for the Pleiotropic Kinase CK2

Number of pages: 84 Posted: 30 Nov 2020

Carrow I. Wells, David H. Drewry, Julie E. Pickett, Amelie Tjaden, Andreas Krämer, Susanne Müller, Laszlo Gyenis, Daniel Menyhart, David W. Litchfield, Stefan Knapp and Alison Donnelly Axtman

University of North Carolina (UNC) at Chapel Hill - Division of Chemical Biology and Medicinal Chemistry, University of North Carolina (UNC) at Chapel Hill - Division of Chemical Biology and Medicinal Chemistry, University of North Carolina (UNC) at Chapel Hill - Division of Chemical Biology and Medicinal Chemistry, Goethe University Frankfurt - Institute of Pharmaceutical Chemistry, Goethe University Frankfurt - Institute of Pharmaceutical Chemistry, Goethe University Frankfurt - Structural Genomics Consortium, Western University - Department of Biochemistry, Western University - Department of Biochemistry, Western University - Department of Biochemistry, Goethe University Frankfurt - Institute of Pharmaceutical Chemistry and University of North Carolina (UNC) at Chapel Hill - Structural Genomics Consortium

Downloads 46 (1,109,210)

Citation 4

Abstract:

3.

Identification and optimization of first-in-class RNA helicase inhibitors

Number of pages: 33 Posted: 09 Jan 2026

Xiaowen Wang, Feijun Wang, Deyu Kong, Dilipkumar Uredi, Fengling Li, Feng Li, Jayachandra Rayadurgam, Hanxuan Li, Esther Wolf, U. Hang Chan, Irene Chau, Hong Zeng, Julia Garcia Perez, Derek J. Wilson, Frances M. Bashore, Xiaodong Wang, Levon Halabelian, Kevin J. Frankowski, Dmitri Kireev and Alison Donnelly Axtman

University of Missouri, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Goethe University Frankfurt - Structural Genomics Consortium, Nanjing University of Science and Technology, affiliation not provided to SSRN, affiliation not provided to SSRN, York University, University of Toronto, University of Toronto, University of Toronto, University of Toronto, York University, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Toronto, affiliation not provided to SSRN, University of Missouri - Columbia and University of North Carolina (UNC) at Chapel Hill - Structural Genomics Consortium

Downloads 40 (1,183,237)

Abstract:

4.

Modulation of Tau Tubulin Kinases ((TTBK1 and TTBK2) Impacts Ciliogenesis

Number of pages: 107 Posted: 19 May 2022

Frances Potjewyd, Ariana B. Marquez, Apirat Chaikuad, Stefanie Howell, Andrea S. Dunn, Alvaro A. Beltran, Jeffery L. Smith, David H. Drewry, Adriana S. Beltran and Alison Donnelly Axtman

University of North Carolina (UNC) at Chapel Hill - Structural Genomics Consortium, University of North Carolina (UNC) at Chapel Hill - Human Pluripotent Stem Cell Core, Goethe University Frankfurt - Institute of Pharmaceutical Chemistry, University of North Carolina (UNC) at Chapel Hill - Structural Genomics Consortium, University of North Carolina (UNC) at Chapel Hill - Department of Pharmacology, University of North Carolina (UNC) at Chapel Hill, School of Medicine, Department of Neuroscience, University of North Carolina (UNC) at Chapel Hill - Structural Genomics Consortium, University of North Carolina (UNC) at Chapel Hill - Structural Genomics Consortium, University of North Carolina (UNC) at Chapel Hill - Human Pluripotent Stem Cell Core and University of North Carolina (UNC) at Chapel Hill - Structural Genomics Consortium

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Alison Donnelly Axtman

University of North Carolina (UNC) at Chapel Hill - Structural Genomics Consortium

University of North Carolina (UNC) at Chapel Hill - Division of Chemical Biology and Medicinal Chemistry

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Scholarly Papers (4)

A Brain-Penetrant PIKfyve Inhibitor Reverses Experimental Neuropathic Pain via Inhibition of Sodium Channels

Abstract:

Development of a Potent and Selective Chemical Probe for the Pleiotropic Kinase CK2

Abstract:

Identification and optimization of first-in-class RNA helicase inhibitors

Abstract:

Modulation of Tau Tubulin Kinases ((TTBK1 and TTBK2) Impacts Ciliogenesis

Abstract: