Author Page for Ann E. Tollefson

Identification of Ebselen Derivatives as Novel SARS-CoV-2 Main Protease Inhibitors: Design, Synthesis, Biological Evaluation, and Structure-Activity Relationships Exploration

Number of pages: 30 Posted: 30 Aug 2023

Heng Zhang, Jing Li, Karoly Toth, Ann E. Tollefson, Lanlan Jing, Shenghua Gao, Xinyong Liu and Peng Zhan

Shandong University, Shandong University, Saint Louis University, Saint Louis University School of Medicine, Shandong University, Shandong University, Shandong University and Shandong University

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Abstract:

2.

Lavr-289, a Broad-Spectrum Antiviral, Protects Immunosuppressed Syrian Hamsters Against Lethal Adenovirus Challenge

Number of pages: 29 Posted: 24 Jun 2025

Ann E. Tollefson, Anna Cline-Smith, Vincent Roy, Luigi A. Agrofoglio, Getahun Abate, Franck Gallardo and Karoly Toth

Saint Louis University School of Medicine, Saint Louis University, University of Orléans, University of Orléans, Saint Louis University - School of Medicine, affiliation not provided to SSRN and Saint Louis University

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Abstract:

3.

Oral Usc-093, a Novel Homoserinamide Analogue of the Tyrosinamide (S)-Hpmpa Prodrug Usc-087 Has Decreased Nephrotoxicity While Maintaining Antiviral Efficacy Against Human Adenovirus Infection of Syrian Hamsters

Number of pages: 25 Posted: 20 Dec 2023

Ann E. Tollefson, Samantha B. Riemann, Baoling Ying, Jacqueline F. Spencer, Justin M. Overhulse, Boris A. Kashemirov, William S.M. Wold, Charles E. McKenna and Karoly Toth

Saint Louis University School of Medicine, University of Southern California, Washington University in St. Louis - Department of Medicine, Saint Louis University, University of Southern California, University of Southern California, Saint Louis University, University of Southern California and Saint Louis University

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Ann E. Tollefson

Saint Louis University School of Medicine

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Scholarly Papers (3)

Identification of Ebselen Derivatives as Novel SARS-CoV-2 Main Protease Inhibitors: Design, Synthesis, Biological Evaluation, and Structure-Activity Relationships Exploration

Abstract:

Lavr-289, a Broad-Spectrum Antiviral, Protects Immunosuppressed Syrian Hamsters Against Lethal Adenovirus Challenge

Abstract:

Oral Usc-093, a Novel Homoserinamide Analogue of the Tyrosinamide (S)-Hpmpa Prodrug Usc-087 Has Decreased Nephrotoxicity While Maintaining Antiviral Efficacy Against Human Adenovirus Infection of Syrian Hamsters

Abstract: