University of Leicester, National Institute for Health Research (NIHR) - Leicester Biomedical Research Centre (BRC), National Institute for Health Research (NIHR) - Leicester Biomedical Research Centre (BRC), University of Leicester, University of Leicester - Leicester Diabetes Centre, University of Leicester - NIHR Leicester Biomedical Research Centre, University of Leicester, University of Leicester, University of Leicester, The Chinese University of Hong Kong (CUHK) - Department of Medicine and Therapeutics, Imperial College London - School of Public Health, University of Leicester - Leicester Diabetes Centre, University of Leicester - Leicester Diabetes Centre and University of Leicester