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Liviu Pirvan

University of Cambridge

Trinity Ln

Cambridge, CB2 1TN

United Kingdom

SCHOLARLY PAPERS

2

DOWNLOADS

90

TOTAL CITATIONS

1

Scholarly Papers (2)

1.

Increased Cholesterol Synthesis Drivesneurotoxicity in Patient Stem Cell-Derived Model of Multiple Sclerosis

Number of pages: 55 Posted: 23 Feb 2024
University of Cambridge, University of Cambridge, University of Colorado, Aurora - Department of Biochemistry and Molecular Genetics, University of Cambridge, University of Cambridge, University of Colorado, Aurora - Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora - Department of Biochemistry and Molecular Genetics, University of Innsbruck, University of Cambridge, University of Cambridge, University of Cambridge, The New York Stem Cell Foundation Research Institute, University of Innsbruck, Fondazione Istituto Italiano di Tecnologia (IIT) - Center for Genomic Science, University of Cologne - Faculty of Medicine, University of Cambridge - Wellcome Trust and MRC Cambridge Stem Cell Institute, University of Colorado, Aurora - Department of Biochemistry and Molecular Genetics and University of Cambridge
Downloads 49 (1,074,648)
Citation 1

Abstract:

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Neuroimmunology, multiple sclerosis, neural stem cells, cellular senescence, cholesterol metabolism, lipid droplets, multi-omics, SASP, neurotoxicity, disease modelling.

2.

Integrative Single-Cell Analysis of Neural Stem/Progenitor Cells Reveals Epigenetically Dysregulated Interferon Response in Progressive Multiple Sclerosis

Number of pages: 58 Posted: 22 Mar 2024
Government of the United States of America - National Institute on Aging (NIA), University of Cambridge, Government of the United States of America - Laboratory of Genetics and Genomics, University of Cambridge, University of Cambridge, University of Cambridge, Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), Government of the United States of America - National Institute on Aging (NIA), University of Cambridge, University of Cambridge, University of Cambridge, Government of the United States of America - Laboratory of Genetics and Genomics, Government of the United States of America - National Institute on Aging (NIA), University of Innsbruck, University of Innsbruck, University of Cambridge, Fondazione Istituto Italiano di Tecnologia (IIT) - Center for Genomic Science, University of Innsbruck, Government of the United States of America - Laboratory of Genetics and Genomics, University of Cambridge - Wellcome Trust and MRC Cambridge Stem Cell Institute, University of Cambridge and Government of the United States of America - National Institute on Aging (NIA)
Downloads 41 (1,170,409)

Abstract:

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Neural stem/progenitor cells, radial glia, single cell/nucleus multiomics, direct reprogramming, RNA sequencing, DNA methylation, senescence, interferon, epigenetics, progressive multiple sclerosis.