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Lun Tan

Sichuan University

No. 24 South Section1, Yihuan Road,

Chengdu, 610064

China

  • Sichuan University

SCHOLARLY PAPERS

2

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84

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Scholarly Papers (2)

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1.

Discovery and Mechanistic Insights into Thieno[3,2-D]Pyrimidine and Heterocyclic Fused Pyrimidines Inhibitors Targeting Tubulin for Cancer Therapy

Number of pages: 43 Posted: 19 Apr 2024
Yuxi Wang, Chengyong Wu, Lele Zhang, Zhilan Zhou, Lun Tan, Zhijia Wang and Cuiyu Guo
Sichuan University, Sichuan University, Sichuan University, Sichuan University, Sichuan University, Sichuan University and Sichuan University
Downloads 54 (1,031,043)

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Tubulin, Colchicine-binding site inhibitor, Crystal structure, thieno[3, 2-d]pyrimidine.

2.

Structure-Guided Design of Potent Tetrazolo[1,5-a]pyrimidine-Based Tubulin Inhibitors with In Vivo Antitumor Activity

Number of pages: 76 Posted: 25 Sep 2025
Yaolin Guo, Quanwei Yu, Cuiyu Guo, Chengyong Wu, Lun Tan, Ruofei Zhang, Yang He, Aiping Tong and Yuxi Wang
affiliation not provided to SSRN, affiliation not provided to SSRN, Sichuan University, affiliation not provided to SSRN, Sichuan University, affiliation not provided to SSRN, Sichuan University, affiliation not provided to SSRN and Sichuan University
Downloads 30 (1,318,317)

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Tubulin, Colchicine-binding site inhibitor, high-throughput virtual screening, crystal structure