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Yaolin Guo

affiliation not provided to SSRN

  • affiliation not provided to SSRN

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Structure-Guided Design of Potent Tetrazolo[1,5-a]pyrimidine-Based Tubulin Inhibitors with In Vivo Antitumor Activity

Number of pages: 76 Posted: 25 Sep 2025
Yaolin Guo, Quanwei Yu, Cuiyu Guo, Chengyong Wu, Lun Tan, Ruofei Zhang, Yang He, Aiping Tong and Yuxi Wang
affiliation not provided to SSRN, affiliation not provided to SSRN, Sichuan University, affiliation not provided to SSRN, Sichuan University, affiliation not provided to SSRN, Sichuan University, affiliation not provided to SSRN and Sichuan University
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Abstract:

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Tubulin, Colchicine-binding site inhibitor, high-throughput virtual screening, crystal structure