- 4th Department of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS - Department of Anesthesia and Intensive Care Medicine, Jena University - Department of Anesthesiology and Intensive Care Medicine, Ludwig Maximilian University of Munich (LMU), National and Kapodistrian University of Athens, Hellenic Institute for the Study of Sepsis, Jena University - Department of Anesthesiology and Intensive Care Medicine, Catholic University of Milan, Ludwig Maximilian University of Munich (LMU) - LMU Klinikum, National and Kapodistrian University of Athens, National and Kapodistrian University of Athens, Tzaneio General Hospital of Piraeus, General Hospital of Thessaloniki "G. Gennimatas" - Intensive Care Unit, “Aghios Dimitrios” Thessaloniki General Hospital - Intensive Care Unit, General Hospital AHEPA, Catholic University of Milan, Asklepieio General Hospital of Voula, University of Crete, Sotiria General Hospital of Chest Diseases, General Hospital AHEPA, Democritus University of Thrace, National and Kapodistrian University of Athens, Swedish Orphan Biovitrum, Catholic University of Milan, Jena University Hospital - Institute for Clinical Chemistry and Laboratory Diagnostics, Aristotle University of Thessaloniki - Hippokration General Hospital and Jena University - Department of Anesthesiology and Intensive Care Medicine