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Shenqin Yao

Allen Institute

SCHOLARLY PAPERS

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Scholarly Papers (1)

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Enhancer-Based AAV Approach for Selective AADC Delivery Reduces Motor Symptoms and Dyskinesia in Parkinson’s Mouse Models

Number of pages: 78 Posted: 17 Feb 2026
Ananya Chowdhury, Alex Fraser, Max Departee, Naz Taskin, Meagan A. Quinlan, John K. Mich, Victoria Omstead, Nathaly Lerma, Ximena Opitz-Araya, Alex C. Hughes, Emily Kussick, Refugio Martinez, Melissa Reding, Elizabeth Liang, Lyudmila Shulga, Dean Rette, Cindy Huang, Brittny Casian, Madison Leibly, Olivia Helback, Tyler Barcelli, Toren Wood, Nicholas Uribe, Colin Bacon, Jessica Bowlus, Dakota Newman, Rana Kutsal, Shannon Khem, Nicholas Donadio, Shenqin Yao, Kara Ronellenfitch, Vonn Wright, Kathryn Gudsnuk, Greg D. Horwitz, Boaz Levi, Ed S. Lein, Jonathan T. Ting and Tanya Daigle
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Abstract:

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AAV, AADC, neurodegeneration, Parkinson's disease, therapy, L-DOPA, striatum, dopamine, nigrostriatal, motor behaviors, locus coeruleus