European Bioinformatics Institute, European Bioinformatics Institute, European Bioinformatics Institute, European Bioinformatics Institute, European Bioinformatics Institute, European Bioinformatics Institute, European Bioinformatics Institute, European Bioinformatics Institute, European Bioinformatics Institute, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Seoul National University, Seoul National University, European Bioinformatics Institute, affiliation not provided to SSRN and European Bioinformatics Institute