affiliation not provided to SSRN, Kamuzu University of Health Sciences, affiliation not provided to SSRN, Kamuzu University of Health Sciences, Washington University Pediatric MS and other Demyelinating Disease Center, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Pennsylvania - Department of Anesthesiology and Critical Care Medicine, Kamuzu University of Health Sciences - Blantyre Malaria Project, affiliation not provided to SSRN, Kamuzu University of Health Sciences - Blantyre Malaria Project, University of Pittsburgh - UPMC Children’s Hospital of Pittsburgh and Kamuzu University of Health Sciences - Blantyre Malaria Project